Rimegepant Impurity 124 CAS CATO-C4X-2487124
| CAS No. | CATO-C4X-2487124 |
| Molecular Formula | C16H16F2N2O |
| Molecular Weight | 290.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Rimegepant Impurity 124 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Rimegepant Impurity 124 (CAS CATO-C4X-2487124, C16H16F2N2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Rimegepant Impurity 124 (C16H16F2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C16H16F2N2O |
| Molecular Weight | 290.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Rimegepant Standards
- Rimegepant Impurity 101 (CAS CATO-C4X-2487101)
- Rimegepant Impurity 128 (CAS CATO-C4X-2487128)
- Rimegepant Impurity 38 (CAS 1373116-05-2)
- Rimegepant Impurity 48 (CAS CATO-C4X-248748)
- Rimegepant Impurity 49 (CAS CATO-C4X-248749)
- Rimegepant Impurity 50 (CAS CATO-C4X-248750)
- Rimegepant Impurity 65 (CAS CATO-C4X-248765)
- Rimegepant Impurity 139 (CAS CATO-C4X-2487139)
Recommended Standards
- Beraprost Impurity 19 (CAS CATO-C4X-218419)
- Etomidate Impurity 50 (CAS 2626887-15-6)
- Calcium Pantothenate EP Impurity E (CAS 897045-90-8)
- 2H-1-Benzopyran-2-one,5,7-dimethoxy-8-[(3-methyl-2-buten-1-yl)oxy]- 96917-26-9 (CAS 96917-26-9)
- Ulipristal Impurity 31 (CAS 54201-84-2)
- Polymyxin Impurity 37 TFA (CAS CATO-C4X-225537)
- Tedizolid Impurity 50 (CAS 1056039-83-8)
- 2-(4-(Morpholinosulfonyl)phenoxy)acetic acid (CAS 36691-78-8)
- 3-(tert-Butoxy)-4-cyclopropoxy-2-fluoropyridine (CAS 1243386-26-6)
- (2R,3R)-3-amino-2-hydroxy-3-(p-tolyl)propanoic acid (CAS 1391437-17-4)
- 4-(trifluoromethyl)thiophene-3-carbaldehyde (CAS 1363512-23-5)
- 2-Amino-N-(2-(dimethylamino)cyclohexyl)-N-isopropylacetamide (CAS 1353951-99-1)
- Epinephrine /Adrenaline Impurity 119 (CAS CATO-C4X-1849119)
- Fragment-[7-31]-Liraglutide (CAS CATO-C4X-199239)
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