Rimegepant Impurity 49 CAS CATO-C4X-248749
| CAS No. | CATO-C4X-248749 |
| Molecular Formula | C16H16F2N2O |
| Molecular Weight | 290.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rimegepant Impurity 49 (CAS CATO-C4X-248749) is a certified pharmaceutical impurity reference standard with the molecular formula C16H16F2N2O and a molecular weight of 290.31 g/mol.
The molecular framework of Rimegepant Impurity 49 (C16H16F2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Rimegepant Impurity 49 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16F2N2O |
| Molecular Weight | 290.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Rimegepant Standards
- Rimegepant Impurity 101 (CAS CATO-C4X-2487101)
- Rimegepant Impurity 124 (CAS CATO-C4X-2487124)
- Rimegepant Impurity 128 (CAS CATO-C4X-2487128)
- Rimegepant Impurity 38 (CAS 1373116-05-2)
- Rimegepant Impurity 48 (CAS CATO-C4X-248748)
- Rimegepant Impurity 50 (CAS CATO-C4X-248750)
- Rimegepant Impurity 65 (CAS CATO-C4X-248765)
- Rimegepant Impurity 139 (CAS CATO-C4X-2487139)
Recommended Standards
- Boc-4-cyano-D-Phe-OH (CAS 146727-62-0)
- Boc-4-cyano-Phe-OH (CAS 131724-45-3)
- 3-(4-Methoxyphenyl)-2-methylindeno[1,2-c]pyrazol-4(2H)-one (CAS 100578-38-9)
- Beraprost Impurity 19 (CAS CATO-C4X-218419)
- Tadalafil Impurity 54 (CAS 171596-32-0)
- Duloxetine Impurity 45 (CAS CATO-C4X-133645)
- Pitolisant Impurity 53 (CAS CATO-C4X-252053)
- (S)-8-(2-Hydroxy-3-methylbut-3-en-1-yl)-7-methoxy-2H-chromen-2-one (CAS 1221-43-8)
- 2-((2-Chloro-6-fluorobenzyl)thio)-3-(furan-2-ylmethyl)-6,7-dimethoxyquinazolin-4(3H)-imine (CAS 439096-22-7)
- 2-((2-(4-Methyl-1H-imidazol-1-yl)ethyl)thio)ethanol (CAS 144396-10-1)
- 2-(Difluoromethyl)-5-iodopyridine-3-acetic acid (CAS 1805309-87-8)
- Methyl 2-(2-cyclopropyl-4-hydroxy-6-methylpyrimidin-5-yl)acetate (CAS 1710293-14-3)
- (R)-3-((2-Fluorobenzyl)oxy)pyrrolidine hydrochloride (CAS 1264035-17-7)
- Peptide 439 (CAS CATO-CPTD788439)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com