Rimegepant Impurity 86 CAS CATO-C4X-248786
| CAS No. | CATO-C4X-248786 |
| Molecular Formula | C28H28F2N6O3 |
| Molecular Weight | 534.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rimegepant Impurity 86 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Rimegepant Impurity 86 (CAS CATO-C4X-248786, C28H28F2N6O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Rimegepant Impurity 86 (C28H28F2N6O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 534.56 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H28F2N6O3 |
| Molecular Weight | 534.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Rimegepant Standards
- Rimegepant (CAS 1289023-67-1)
- Rimegepant Impurity 127 (CAS CATO-C4X-2487127)
- Rimegepant Impurity 153 (CAS CATO-C4X-2487153)
- Rimegepant Impurity 39 (CAS CATO-C4X-248739)
- Rimegepant Impurity 40 (CAS CATO-C4X-248740)
- Rimegepant Impurity 41 (CAS CATO-C4X-248741)
- Rimegepant Impurity 42 (CAS CATO-C4X-248742)
- Rimegepant Impurity 43 (CAS CATO-C4X-248743)
Recommended Standards
- Rimegepant Impurity 82 (CAS CATO-C4X-248782)
- Rimegepant Impurity 92 (CAS CATO-C4X-248792)
- Rimegepant Impurity 67 (CAS CATO-C4X-248767)
- Rimegepant Impurity 93 (CAS CATO-C4X-248793)
- Chlorpromazine Hydrochloride EP Impurity F (CAS 72372-62-4)
- Valaciclovir Impurity 56 (CAS CATO-C4X-124856)
- Flomoxef Impurity 59 (CAS 2095489-25-9)
- 1-benzyl-1-methylurea (CAS 73355-62-1)
- Zimlovisertib (CAS 1817626-54-2)
- Ethyl 4-(8-methoxy-4-(o-tolylamino)quinolin-3-yl)-4-oxobutanoate (CAS 150907-43-0)
- 2-(Isopentyloxy)cyclohexan-1-amine (CAS 1038320-57-8)
- 5-Chloro-2-(1-chloroethyl)-3-fluoropyridine (CAS 1637310-94-1)
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