Dotinurad Impurity 229 CAS CATO-C4X-2494229
| CAS No. | CATO-C4X-2494229 |
| Molecular Formula | C14H10ClNO3S |
| Molecular Weight | 307.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Dotinurad Impurity 229 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Dotinurad Impurity 229 (CAS CATO-C4X-2494229) is a certified pharmaceutical impurity reference standard with the molecular formula C14H10ClNO3S and a molecular weight of 307.75 g/mol.
Structurally, Dotinurad Impurity 229 (C14H10ClNO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 307.75 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H10ClNO3S |
| Molecular Weight | 307.75 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dotinurad Standards
- Dotinurad Impurity 123 (CAS 888731-24-6)
- Dotinurad Impurity 184 (CAS CATO-C4X-2494184)
- Dotinurad Impurity 44 (CAS CATO-C4X-249444)
- Dotinurad Impurity 90 (CAS CATO-C4X-249490)
- Dotinurad Impurity 140 (CAS CATO-C4X-2494140)
- Dotinurad Impurity 48 (CAS CATO-C4X-249448)
- Dotinurad Impurity 255 (CAS CATO-C4X-2494255)
- Dotinurad Impurity 50 (CAS CATO-C4X-249450)
Recommended Standards
- Tianeptine EP Impurity C (CAS 26638-53-9)
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- tert-Butyl (5-chloro-2-(methylsulfonyl)pyrimidin-4-yl)carbamate (CAS 955112-59-1)
- 4-Chloro-5-tosyl-5H-pyrrolo[3,2-d]pyrimidine (CAS 1311275-32-7)
- Nicardipine Impurity 64 (CAS CATO-C4X-171064)
- Amoxicillin Impurity 17 (CAS 1313237-94-3)
- Methotrexate Impurity 28 (CAS 5939-37-7)
- Tofacitinib Impurity 82 (CAS 1229041-97-7)
- 2,3-Dimethylbenzene-1,4-diamine (CAS 5306-96-7)
- ethyl 1,4-diazabicyclo[3.2.2]nonane-3-carboxylate (CAS 2089677-94-9)
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- 5-(4,6-Di((1R,5S)-3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-1,3,5-triazin-2-yl)-4-(difluoromethyl)pyridin-2-amine (CAS 1927857-56-4)
- 2,6-Dimethylphenanthrene (CAS 17980-16-4)
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