Dotinurad Impurity 249 CAS CATO-C4X-2494249
| CAS No. | CATO-C4X-2494249 |
| Molecular Formula | C16H8Cl4O6 |
| Molecular Weight | 438.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Dotinurad Impurity 249 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Dotinurad Impurity 249 (CAS CATO-C4X-2494249), a pharmacopoeial impurity reference standard (molecular formula C16H8Cl4O6, MW 438.04 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C16H8Cl4O6, Dotinurad Impurity 249 contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 438.04 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H8Cl4O6 |
| Molecular Weight | 438.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 95 |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Dotinurad Standards
- Dotinurad Impurity 74 (CAS CATO-C4X-249474)
- Dotinurad Impurity 230 (CAS CATO-C4X-2494230)
- Dotinurad Impurity 252 (CAS CATO-C4X-2494252)
- Dotinurad Impurity 236 (CAS CATO-C4X-2494236)
- Dotinurad Impurity 70 (CAS CATO-C4X-249470)
- Dotinurad Impurity 34 (CAS CATO-C4X-249434)
- Dotinurad Impurity 8 (CAS 1285573-40-1)
- Dotinurad Impurity 102 (CAS CATO-C4X-2494102)
Recommended Standards
- (2 β,3α,5α)-21-Chloro-3-hydroxy-2-(4-morpholinyl)-pregnan-20-one (CAS 156685-94-8)
- 3,5-Dichloro-2-(tributylstannyl)pyrazine (CAS 446285-70-7)
- Sulbactam Impurity 34 (CAS CATO-C4X-175634)
- 3-((4-Chlorobenzyl)thio)-5-(4,5-dihydronaphtho[1,2-b]thiophen-2-yl)-4-ethyl-4H-1,2,4-triazole (CAS 477887-85-7)
- Ornidazole Impurity 4 (CAS 62580-80-7)
- Sivelestat sodium impurity 22 (CAS 1655497-02-1)
- Pemetrexed Impurity 61 (CAS CATO-C4X-172661)
- 3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline (CAS 5423-67-6)
- 5-(4-Methoxyphenyl)-4-((4-(trifluoromethyl)phenyl)diazenyl)-1H-pyrazole (CAS 338414-26-9)
- Cefprozil Δ3 Isomer (CAS 1000980-59-5)
- 2-(Piperidin-4yl)acetic acidHCl (CAS 73415-84-6)
- 1-(3-Methylthiophen-2-yl)propan-1-ol (CAS 1250931-69-1)
- Methyl 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-2-carboxylate (CAS 1025719-02-1)
- Osteoblast Activating Peptide (mouse, rat) (H-7262.0500) (CAS 1222950-80-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com