Dotinurad Impurity 8 CAS 1285573-40-1
| CAS No. | 1285573-40-1 |
| Molecular Formula | C15H8Cl2F3NO4S |
| Molecular Weight | 426.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Dotinurad Impurity 8 (CAS 1285573-40-1), a pharmacopoeial impurity reference standard (molecular formula C15H8Cl2F3NO4S, MW 426.19 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C15H8Cl2F3NO4S, Dotinurad Impurity 8 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 426.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dotinurad Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H8Cl2F3NO4S |
| Molecular Weight | 426.19 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dotinurad Standards
- Dotinurad Impurity 75 (CAS 24526-98-5)
- Dotinurad Impurity 34 (CAS CATO-C4X-249434)
- Dotinurad Impurity 70 (CAS CATO-C4X-249470)
- Dotinurad Impurity 236 (CAS CATO-C4X-2494236)
- Dotinurad Impurity 197 (CAS CATO-C4X-2494197)
- Dotinurad Impurity 252 (CAS CATO-C4X-2494252)
- Dotinurad Impurity 230 (CAS CATO-C4X-2494230)
- Dotinurad Impurity 249 (CAS CATO-C4X-2494249)
Recommended Standards
- 6-Methoxy-2-(tributylstannyl)nicotinaldehyde (CAS 2265921-90-0)
- 2-Ethoxy-4-formyl-6-iodophenyl 4-methoxybenzoate (CAS 443730-63-0)
- Ethyl 2-(diethoxyphosphoryl)-2-(4-iodophenyl)acetate (CAS 152302-87-9)
- 3-((2-Ethoxy-4-formyl-6-iodophenoxy)methyl)benzoic acid (CAS 428501-72-8)
- Mivacurium chloride Impurity 25 (CAS 104758-49-8（free base）)
- Benidipine Impurity 5 (CAS CATO-C4X-11205)
- Methylprednisolone impurity 92 (CAS CATO-C4X-191992)
- (S)-2-(Piperidin-3-yl)isoindolin-1-one hydrochloride (CAS 1786622-63-6)
- n-Cyclobutyl-2-fluoro-5-methylaniline (CAS 1250698-67-9)
- 1-Amino-3-(2,2,2-trifluoroethyl)thiourea (CAS 1092300-87-2)
- (4-(Benzo[d]thiazol-2-yl)piperazin-1-yl)(1-(thiophen-2-ylsulfonyl)piperidin-4-yl)methanone (CAS 900001-14-1)
- GANODERMATRIOL (CAS 105300-28-5)
- 1-methoxycyclohexane-1-carbonitrile (CAS 83268-57-9)
- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com