Venetoclax Impurity 152 CAS CATO-C4X-2495152
| CAS No. | CATO-C4X-2495152 |
| Molecular Formula | C19H29BN2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Venetoclax Impurity 152 (CAS CATO-C4X-2495152), a pharmacopoeial impurity reference standard (molecular formula C19H29BN2O2HCl, MW 364.72 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Venetoclax Impurity 152 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 364.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H29BN2O2 2*HCl |
| Molecular Weight | 364.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Venetoclax Standards
Recommended Standards
- Cefamandole Impurity 11 (CAS CATO-C4X-122111)
- Terbutaline Impurity 24 (CAS CATO-C4X-118324)
- Lenalidomide Impurity 29 (CAS 31140-42-8)
- 2-(Aminomethyl)-6-(difluoromethyl)-5-hydroxypyridine-3-methanol (CAS 1806947-11-4)
- 1-((Tetrahydrofuran-3-yl)methyl)-1H-pyrazol-4-amine hydrochloride (CAS 1431963-89-1)
- Fuscaxanthone C (CAS 15404-76-9)
- 4-Acetamido-2-fluoro-5-methylbenzenesulfonyl chloride (CAS 71245-49-3)
- N-(2-Hydroxy-3-methoxy-2-methylpropyl)-[1,1'-biphenyl]-4-carboxamide (CAS 1334372-12-1)
- Tofacitinib Impurity 5 (CAS 1616760-97-4)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
Why CATO?
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