Venetoclax Impurity 1 CAS 1228779-96-1
| CAS No. | 1228779-96-1 |
| Molecular Formula | C12H17N3O5S |
| Molecular Weight | 315.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Venetoclax Impurity 1 (CAS 1228779-96-1) is a certified pharmaceutical impurity reference standard with the molecular formula C12H17N3O5S and a molecular weight of 315.35 g/mol.
Structurally, Venetoclax Impurity 1 (C12H17N3O5S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 315.35 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Venetoclax Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H17N3O5S |
| Molecular Weight | 315.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Venetoclax Standards
- Venetoclax Impurity 102 (CAS CATO-C4X-2495102)
- Venetoclax Impurity 103 (CAS CATO-C4X-2495103)
- Venetoclax Impurity 117 (CAS CATO-C4X-2495117)
- Venetoclax Impurity 123 (CAS CATO-C4X-2495123)
- Venetoclax Impurity 90 (CAS CATO-C4X-249590)
- Venetoclax Impurity 136 (CAS CATO-C4X-2495136)
- Venetoclax Impurity 138 (CAS CATO-C4X-2495138)
- Venetoclax Impurity 133 (CAS CATO-C4X-2495133)
Recommended Standards
- Nicorandil impurity 68 (CAS CATO-C4X-190768)
- Imipenem Impurity 116 (CAS CATO-C4X-1662116)
- Entacapone Impurity 23 (CAS 1185241-19-3)
- p-Hydroxyfenbendazole (CAS 72447-64-4)
- Tadalafil Impurity 20 (CAS 171752-68-4)
- Avatrombopag Impurity 113 (CAS CATO-C4X-2234113)
- Treprostinil Impurity 4 (CAS CATO-C4X-21164)
- Zopiclone Impurity 2 (CAS 13606-92-3)
- 3-(4-Iodophenyl)-1H-pyrazole (CAS 1019007-92-1)
- 2,4-Dichloro-N-((5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)-N-(4-methoxyphenyl)benzenesulfonamide (CAS 957041-78-0)
- 2-Amino-4-(difluoromethyl)-5-methoxypyridin-3-ol (CAS 1805328-08-8)
- 2-(2,4,6-Trichloro-3,5-dimethylphenoxy)acetic acid (CAS 19545-98-3)
- 2-(1H-indol-3-yl)cyclohexan-1-amine (CAS 4765-27-9)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com