Venetoclax Impurity 88 CAS CATO-C4X-249588
| CAS No. | CATO-C4X-249588 |
| Molecular Formula | C13H23ClN2 |
| Molecular Weight | 242.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Venetoclax Impurity 88 (CAS CATO-C4X-249588, C13H23ClN2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrile group, chlorine substitution, Venetoclax Impurity 88 is typically white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 242.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H23ClN2 |
| Molecular Weight | 242.79 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Venetoclax Standards
- Venetoclax Impurity 125 (CAS CATO-C4X-2495125)
- Venetoclax Impurity 109 (CAS CATO-C4X-2495109)
- Venetoclax Impurity 118 (CAS CATO-C4X-2495118)
- Venetoclax Impurity 140 (CAS CATO-C4X-2495140)
- Venetoclax Impurity 150 (CAS CATO-C4X-2495150)
- Venetoclax Impurity 148 (CAS CATO-C4X-2495148)
- Venetoclax Impurity 137 (CAS CATO-C4X-2495137)
- Venetoclax Impurity 74 (CAS CATO-C4X-249574)
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