Venetoclax Impurity 84 CAS CATO-C4X-249584
| CAS No. | CATO-C4X-249584 |
| Molecular Formula | C19H26ClN3O |
| Molecular Weight | 347.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Venetoclax Impurity 84 (CAS CATO-C4X-249584, C19H26ClN3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Venetoclax Impurity 84 (C19H26ClN3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Venetoclax Impurity 84 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H26ClN3O |
| Molecular Weight | 347.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥98% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Venetoclax Standards
- Venetoclax Impurity 52 (CAS CATO-C4X-249552)
- Venetoclax Impurity 79 (CAS CATO-C4X-249579)
- Venetoclax Impurity 14 (CAS CATO-C4X-249514)
- Venetoclax Impurity 49 (CAS CATO-C4X-249549)
- Venetoclax Impurity 126 (CAS CATO-C4X-2495126)
- Venetoclax Impurity 130 (CAS CATO-C4X-2495130)
- Venetoclax Impurity 97 (CAS CATO-C4X-249597)
- Venetoclax Impurity 98 (CAS CATO-C4X-249598)
Recommended Standards
- Sarpogrelate Impurity 27 (CAS CATO-C4X-291327)
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- 1-[(4-tert-Butylphenyl)amino]-3-(4-chlorophenoxy)-2-methylpropan-2-ol (CAS 866156-86-7)
- Rimegepant Impurity 59 (CAS 1190363-47-3)
- Desmopressin EP Impurity D TFA salt (CAS CATO-C4X-22154)
- Relebactam Impurity 32 (CAS CATO-C4X-214432)
- 1-(3,4-Dichlorophenyl)piperidine-4-carboxylic acid (CAS 847407-54-9)
- LiBPP (CAS 1049805-81-3)
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- N-(2-aminoethyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide hydrochloride (CAS 1828966-95-5)
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- 5-(2,5-Dimethylphenoxymethyl)-1,3,4-oxadiazole-2-thiol (CAS 141333-82-6)
- Palmitoyl Tripeptide-8 TFA salt (CAS 936544-53-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com