Pitolisant impurity 36 CAS CATO-C4X-252036
| CAS No. | CATO-C4X-252036 |
| Molecular Formula | C17H27ClNO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Pitolisant impurity 36 (CAS CATO-C4X-252036, C17H27ClNOCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Pitolisant impurity 36 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 332.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Pitolisant impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H27ClNO Cl |
| Molecular Weight | 332.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Pitolisant Standards
- Pitolisant impurity 22 (CAS 110129-10-7)
- Pitolisant impurity 02 (CAS 157355-75-4)
- Pitolisant impurity 25 (CAS 2307451-04-1)
- Pitolisant-D6 HCl (CAS 2416991-78-9)
- Pitolisant impurity 39 (CAS 2858590-15-3)
- Pitolisant impurity 16 (CAS 31951-46-9)
- Pitolisant impurity 7 (CAS 362665-54-1)
- Pitolisant (CAS 362665-56-3)
Recommended Standards
- Minocycline Impurity 43 (CAS 28698-94-4)
- Levosimendan Impurity 67 (CAS CATO-C4X-130867)
- Hydroxychloroquine Impurity 71 Sulfate (CAS 2411340-31-1 (free base))
- 3-Oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carbaldehyde (CAS 935758-15-9)
- 3-(hydroxymethyl)-2,2,5,5-tetramethylpyrrolidin-1-ol (CAS 1020718-52-8)
- N-(2-(3-(4-Fluorobenzyl)ureido)phenyl)-2-(trifluoromethyl)benzamide (CAS 1202981-00-7)
- 1-(4-BRomo-2-chlorophenyl)guanidine (CAS 1249016-90-7)
- 1-(4-(5-Isopropyl-1,3,4-oxadiazol-2-yl)piperidin-1-yl)-2-(thiophen-2-yl)ethan-1-one (CAS 1209943-12-3)
- Chlorfenac (CAS 85-34-7)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
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