Apalutamide Impurity 115（E-Isomer） CAS CATO-C4X-2749115
| CAS No. | CATO-C4X-2749115 |
| Molecular Formula | C15H5F6N5 |
| Molecular Weight | 369.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Apalutamide Impurity 115（E-Isomer） (C15H5F6N5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Apalutamide Impurity 115（E-Isomer） (CAS CATO-C4X-2749115) is a certified pharmaceutical impurity reference standard with the molecular formula C15H5F6N5 and a molecular weight of 369.22 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H5F6N5 |
| Molecular Weight | 369.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Apalutamide Standards
- Apalutamide Impurity 17 (CAS CATO-C4X-274917)
- Apalutamide Impurity 114 (CAS CATO-C4X-2749114)
- Apalutamide Impurity 18 (CAS CATO-C4X-274918)
- Apalutamide impurity 85 (CAS CATO-C4X-274985)
- Apalutamide Impurity 28 (CAS CATO-C4X-274928)
- Apalutamide Impurity 113 (CAS CATO-C4X-2749113)
- Apalutamide impurity 82 (CAS 2393949-01-2)
- Apalutamide Impurity 74 (CAS CATO-C4X-274974)
Recommended Standards
- Perfluorophenyl 3-nitrobenzenesulfonate (CAS 663175-93-7)
- dCeMM1 (CAS 118719-16-7)
- Perfluorophenyl 2-nitrobenzenesulfonate (CAS 885950-33-4)
- Ethyl 4-(4-bromophenyl)sulfonylbenzoate (CAS 141212-53-5)
- Dipyridamole EP Impurity B (CAS 16908-47-7)
- Orbifloxacin EP Impurity A (CAS CATO-C4X-25672)
- Troxipide Impurity 27 (CAS 30751-15-6)
- n-(2-Methoxy-5-nitrophenyl)-2-((4-methyl-4h-1,2,4-triazol-3-yl)thio)acetamide (CAS 379710-27-7)
- Mianserin Impurity 89 (CAS CATO-C4X-136989)
- 1-Allyl-4,5-dimethyl-3-(phenylsulfonyl)-1H-pyrrol-2-amine (CAS 1269534-89-5)
- 2-(Chloromethyl)-6-methylpyridine Hydrochloride (CAS 3099-30-7)
- (2E)-1-(4-Ethylphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one (CAS 1175880-73-5)
- 2-(Morpholinomethyl)isoindoline-1,3-dione (CAS 6857-12-1)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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