Apalutamide Impurity 28 CAS CATO-C4X-274928
| CAS No. | CATO-C4X-274928 |
| Molecular Formula | C16H13BrF2N2O2 |
| Molecular Weight | 383.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Apalutamide Impurity 28 (CAS CATO-C4X-274928) is a certified pharmaceutical impurity reference standard with the molecular formula C16H13BrF2N2O2 and a molecular weight of 383.19 g/mol.
Based on its molecular formula C16H13BrF2N2O2, Apalutamide Impurity 28 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 383.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13BrF2N2O2 |
| Molecular Weight | 383.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Apalutamide Standards
- Apalutamide impurity 85 (CAS CATO-C4X-274985)
- Apalutamide Impurity 18 (CAS CATO-C4X-274918)
- Apalutamide Impurity 114 (CAS CATO-C4X-2749114)
- Apalutamide Impurity 17 (CAS CATO-C4X-274917)
- Apalutamide Impurity 115（E-Isomer） (CAS CATO-C4X-2749115)
- Apalutamide Impurity 74 (CAS CATO-C4X-274974)
- Apalutamide Impurity 23 (CAS CATO-C4X-274923)
- Apalutamide Impurity 100 (CAS CATO-C4X-2749100)
Recommended Standards
- 6-Bromo-3-(4-fluorobenzenesulfonyl)-2H-chromen-2-one (CAS 904438-70-6)
- Methyl 3-((tert-butoxycarbonyl)amino)-5-iodothiophene-2-carboxylate (CAS 1007171-35-8)
- 3-(1-(2-Bromo-5-methoxybenzoyl)pyrrolidin-3-yl)oxazolidine-2,4-dione (CAS 2034383-51-0)
- 1-((4-Bromo-2-methyl-5-oxo-1-phenyl-2,5-dihydro-1H-pyrazol-3-yl)methyl)-1H-imidazole-4,5-dicarbonitrile (CAS 1024232-73-2)
- Atorvastatin Impurity 141 Calcium Salt (CAS 1046378-58-8)
- Lefamulinum Impurity 11 (CAS CATO-C4X-304711)
- Ilaprazole Impurity 104 (CAS CATO-C4X-1130104)
- Milnacipran Impurity 10 (CAS CATO-C4X-103310)
- 2-Cyclohexyl-1-(pyrimidin-2-yl)ethan-1-one (CAS 1249454-39-4)
- tert-Butyl 3-amino-1H-indole-2-carboxylate (CAS 165107-89-1)
- 2-Amino-N-[(4-methoxyphenyl)methyl]acetamide (CAS 57459-57-1)
- Diethyl Oxalate (CAS 95-92-1)
- Triethyl OrthoforMate (ForMyl-13C) (CAS 118659-62-4)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com