Apalutamide Impurity 27 CAS CATO-C4X-274927
| CAS No. | CATO-C4X-274927 |
| Molecular Formula | C27H34F3N5O6 |
| Molecular Weight | 581.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 581.58 g/mol gives Apalutamide Impurity 27 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Apalutamide Impurity 27 (CAS CATO-C4X-274927) is a certified pharmaceutical impurity reference standard with the molecular formula C27H34F3N5O6 and a molecular weight of 581.58 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Apalutamide Impurity 27 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 581.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H34F3N5O6 |
| Molecular Weight | 581.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Apalutamide Standards
- Apalutamide Impurity 29 (CAS CATO-C4X-274929)
- Apalutamide Impurity 119 (CAS CATO-C4X-2749119)
- Apalutamide Impurity 32 (CAS CATO-C4X-274932)
- Apalutamide Impurity 107 (CAS CATO-C4X-2749107)
- Apalutamide Impurity 9 (CAS 2894796-78-0)
- Apalutamide Impurity 31 (CAS CATO-C4X-274931)
- Apalutamide Impurity 105 (CAS CATO-C4X-2749105)
- Apalutamide Impurity 98 (CAS CATO-C4X-274998)
Recommended Standards
- Streptomycin (CAS 57-92-1)
- Kanamycin B Sulfate (CAS 29701-07-3)
- Vonoprazan Impurity 227 (CAS CATO-C4X-1020227)
- 2,4,6-Tris(perfluorophenyl)-1,3,5,2,4,6-trioxatriborinane (CAS 223440-98-0)
- Ceftazidime Impurity 88 (CAS CATO-C4X-121288)
- Amorolfine Impurity 52 (CAS CATO-C4X-154252)
- Econazole impurity 23 (CAS 1165796-83-7)
- 9(11), (5β)-CHOLENIC ACID-3α-OL-12-ONE METHYL ESTER (CAS 65065-56-7)
- 3-(2,5-Dimethylbenzenesulfonyl)-4,6-dimethyl-1,2-dihydropyridin-2-one (CAS 860787-70-8)
- 3-(trifluoromethyl)pyrrolidine hydrochloride (CAS 1189485-03-7)
- 6-Amino-2-methylnicotinonitrile (CAS 183428-90-2)
- N-(5-(Methylthio)-1,3,4-thiadiazol-2-yl)-1-(thiophen-2-yl)cyclopentane-1-carboxamide (CAS 1219912-21-6)
- 2-(2-Methyl-1h-benzo[d]imidazol-1-yl)ethan-1-amine hydrochloride (CAS 1193387-77-7)
- [3,5 Diiodo-Tyr7] Peptide T (CAS 128551-40-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com