Apalutamide Impurity 35 CAS CATO-C4X-274935
| CAS No. | CATO-C4X-274935 |
| Molecular Formula | C21H16F4N4O4S |
| Molecular Weight | 496.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Apalutamide Impurity 35 (CAS CATO-C4X-274935), a pharmacopoeial impurity reference standard (molecular formula C21H16F4N4O4S, MW 496.43 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C21H16F4N4O4S, Apalutamide Impurity 35 contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 496.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Apalutamide Impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H16F4N4O4S |
| Molecular Weight | 496.43 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Apalutamide Standards
- Apalutamide Impurity 1 (CAS CATO-C4X-27491)
- Apalutamide Impurity 13 (CAS 2649802-40-2)
- Apalutamide Impurity 22 (CAS CATO-C4X-274922)
- Apalutamide Impurity 102 (CAS CATO-C4X-2749102)
- Apalutamide Impurity 112 (CAS CATO-C4X-2749112)
- Apalutamide Impurity 10 (CAS CATO-C4X-274910)
- Apalutamide Impurity 68 (CAS CATO-C4X-274968)
- Apalutamide Impurity 5 (CAS CATO-C4X-27495)
Recommended Standards
- 1-(4-Phenyl-1,3-thiazol-2-yl)-5-(trifluoromethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}-1H-pyrazole-4-carboxamide (CAS 321998-60-1)
- Ethyl 5-(2-(2-oxo-2-((2-(trifluoromethyl)phenyl)amino)acetyl)-1H-pyrrol-1-yl)-1-phenyl-1H-pyrazole-4-carboxylate (CAS 477709-30-1)
- (2S)-2-Amino-3-(6-chloro-1H-indol-3-yl)-1-(5-((5-chloro-1H-indol-3-yl)methyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)propan-1-one (CAS 2228955-02-8)
- Roflumilast Impurity 46 (CAS CATO-C4X-108446)
- Leuprorelin Impurity 56 (CAS CATO-C4X-182256)
- Zoledronic Acid Impurity 6 (CAS 17450-34-9)
- Formoterol Impurity 87 (CAS CATO-C4X-152587)
- 4-Chloro-N'-(pyridin-3-yl)benzimidamide (CAS 144657-95-4)
- 3-(2-(2,4-Dichlorophenyl)acetamido)propanoic acid (CAS 53056-15-8)
- 6-(4-Formylpiperazin-1-yl)-4-methylnicotinonitrile (CAS 1355232-07-3)
- Bis(2-methyl-8-hydroxyquinolinato)zinc (CAS 14128-73-5)
- Methyl (2-imino-1,3-thiazolidin-3-yl)acetate hydrobromide (CAS 138404-38-3)
- 3-Bromo-5-cyclopropoxyaniline (CAS 1243321-64-3)
- Retatrutide (CAS 2381089-83-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com