Alectinib Impurity 43 CAS CATO-C4X-283643

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-283643
Molecular FormulaC25H28N2O5S
Molecular Weight468.57 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Alectinib Impurity 43 CAS CATO-C4X-283643 chemical structure

Description

The occurrence of Alectinib Impurity 43 is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Alectinib Impurity 43 (CAS CATO-C4X-283643) is a certified pharmaceutical impurity reference standard with the molecular formula C25H28N2O5S and a molecular weight of 468.57 g/mol.

Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Alectinib Impurity 43 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 468.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Alectinib Impurity 43 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC25H28N2O5S
Molecular Weight468.57 g/mol
Purity≥95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms2
Sulfur Atoms1

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