Fedratinib Impurity 6 CAS 936091-39-3
| CAS No. | 936091-39-3 |
| Molecular Formula | C23H28N6O3S |
| Molecular Weight | 468.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Fedratinib Impurity 6 (CAS 936091-39-3), a pharmacopoeial impurity reference standard (molecular formula C23H28N6O3S, MW 468.57 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Fedratinib Impurity 6 (C23H28N6O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Fedratinib Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H28N6O3S |
| Molecular Weight | 468.57 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Fedratinib Standards
Recommended Standards
- Alectinib Impurity 43 (CAS CATO-C4X-283643)
- 23,24,25,26-Tetranoroleana-1(10),3,5,7-tetraen-29-oic acid, 3,4,6-trihydroxy-9,13-dimethyl-2-oxo-, (9beta,13alpha,14beta,20alpha)- (CAS 1253387-35-7)
- Evatanepag (CAS 223488-57-1)
- Norethindrone Impurity 27 (CAS 142154-46-9)
- Dalilesen impurity 27 (CAS CATO-C4X-301027)
- Lumateperone Impurity 34 (CAS 51787-87-2)
- Valsartan Impurity 144 (CAS 149690-12-0)
- 2-Ethoxy-5-[(4-phenylpiperidin-1-yl)sulfonyl]benzoic acid (CAS 866156-11-8)
- Edrophonium chloride (CAS 116-38-1)
- 2-Amino-5-nitro-2-fluorobenzophenone (CAS 344-80-9)
- 8-Fluoro-7-(trifluoromethyl)chroman-4-one (CAS 890840-06-9)
- O-(2-Cyclopropylbenzyl)hydroxylamine (CAS 1388074-11-0)
- 3-Ethyl-4-(hydroxymethyl)phenylboronic acid (CAS 2121514-80-3)
- D-Lys16-Tirzepatide (CAS CATO-CPTD788918)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com