Alectinib Impurity 57 CAS CATO-C4X-283657
| CAS No. | CATO-C4X-283657 |
| Molecular Formula | C25H28INO3 |
| Molecular Weight | 517.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Alectinib Impurity 57 (CAS CATO-C4X-283657, C25H28INO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution, Alectinib Impurity 57 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 517.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Alectinib Impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H28INO3 |
| Molecular Weight | 517.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Alectinib Standards
- Alectinib impurity 25 (CAS CATO-C4X-283625)
- Alectinib Impurity 51 (CAS CATO-C4X-283651)
- Alectinib Impurity 80 (CAS CATO-C4X-283680)
- Alectinib Impurity 84 (CAS CATO-C4X-283684)
- Alectinib Impurity 13 (CAS 1256585-29-1)
- Alectinib Impurity 79 (CAS CATO-C4X-283679)
- Alectinib Impurity 61 (CAS CATO-C4X-283661)
- Alectinib Impurity 9 (CAS CATO-C4X-28369)
Recommended Standards
- Folic Acid Impurity 46 Disodium Salt (CAS 914800-65-0)
- 1,8-Diamino-2,7-dichloro-4,5-bis(p-tolylamino)anthracene-9,10-dione (CAS 83578-94-3)
- (S)-4-(1-(3-(3,5-dichlorophenyl)-5-(6-methoxynaphthalen-2-yl)-1H-pyrazol-1-yl)ethyl)benzoic acid (CAS 870823-11-3)
- N-(2,4-dinitro-6-(trifluoromethyl)phenyl)-2,3,5,6,8,9,11,12-octahydrobenzo[b][1,4,7,10,13]pentaoxacyclopentadecin-15-amine (CAS 78857-86-0)
- Finerenone Impurity 69 (CAS CATO-C4X-288069)
- Perospirone Impurity 16 (CAS CATO-C4X-245816)
- Varenicline Impurity 5 (CAS 950781-89-2)
- 5,6-Bis((4-fluorophenyl)amino)isoindoline-1,3-dione (CAS 145915-60-2)
- 2,3-Dichloro-5-cyclopropylpyridine (CAS 2260845-27-8)
- Ethyl 1-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)piperidine-4-carboxylate (CAS 135127-54-7)
- N-(4-chloro-2-methylphenyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide (CAS 861208-49-3)
- 2-(Chloromethyl)-1-phenyl-1H-benzimidazole (CAS 94937-86-7)
- (1-Methylpiperidin-4-yl)methyl 4-methylbenzenesulfonate (CAS 1353946-73-2)
- Peptide Impurity 26 (CAS 1350456-66-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com