Alectinib Impurity 81 CAS CATO-C4X-283681
| CAS No. | CATO-C4X-283681 |
| Molecular Formula | C25H29IN2O4 |
| Molecular Weight | 548.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Alectinib Impurity 81 (CAS CATO-C4X-283681) is a certified pharmaceutical impurity reference standard with the molecular formula C25H29IN2O4 and a molecular weight of 548.41 g/mol.
The molecular framework of Alectinib Impurity 81 (C25H29IN2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Alectinib Impurity 81 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H29IN2O4 |
| Molecular Weight | 548.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Alectinib Standards
- Alectinib impurity 26 (CAS CATO-C4X-283626)
- Alectinib Impurity 11 (CAS 1256698-41-5)
- Alectinib impurity 29 (CAS 1256585-30-4)
- Alectinib impurity 20 (CAS 2287185-55-9)
- Alectinib Impurity 34 (CAS 2412921-45-8)
- Alectinib Impurity 41 (CAS CATO-C4X-283641)
- Alectinib impurity 30 (CAS CATO-C4X-283630)
- Alectinib Impurity 76 (CAS CATO-C4X-283676)
Recommended Standards
- Citicoline Impurity 18 (CAS CATO-C4X-220318)
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- (2S)-2-Amino-5-(((2R)-1-((carboxymethyl)amino)-3-((2-((4-(hydroxyhydroarsoryl)phenyl)amino)-2-oxoethyl)thio)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid (CAS 334756-34-2)
- (2-Methyl-2-propanethiolato)(triphenylphosphine)gold (CAS 122711-31-3)
- Nebivolol Hydrochloride EP Impurity A (CAS 1696472-15-7)
- Riociguat Impurity 16 (CAS 1361569-18-7)
- Finerenone Impurity 23 (CAS CATO-C4X-288023)
- 4-(2,2-Difluoroethoxy)benzene-1-sulfonyl chloride (CAS 954369-07-4)
- Iomeprol Impurity 13 (CAS CATO-C4X-182013)
- ethyl 2-(5-chlorothiophen-2-yl)acetate (CAS 1123190-96-4)
- Ethyl N-[[(5-chloro-2-pyridinyl)amino]thioxomethyl]carbamate (CAS 78852-50-3)
- [1-(1-Benzofuran-2-carbonyl)piperidin-4-yl]methanamine (CAS 1283004-62-5)
- Tert-butyl 1H-pyrrolo[3,2-c]pyridine-6-carboxylate (CAS 868171-72-6)
- Tumor Targeted Pro-Apoptotic Peptide (CAS 1926163-30-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com