Alectinib Impurity 76 CAS CATO-C4X-283676
| CAS No. | CATO-C4X-283676 |
| Molecular Formula | C25H27IN2O3 |
| Molecular Weight | 530.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 530.40 g/mol gives Alectinib Impurity 76 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Alectinib Impurity 76 (CAS CATO-C4X-283676) is a certified pharmaceutical impurity reference standard with the molecular formula C25H27IN2O3 and a molecular weight of 530.40 g/mol.
Alectinib Impurity 76 (C25H27IN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Alectinib Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H27IN2O3 |
| Molecular Weight | 530.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Alectinib Standards
- Alectinib Impurity 62 (CAS CATO-C4X-283662)
- Alectinib impurity 30 (CAS CATO-C4X-283630)
- Alectinib Impurity 79 (CAS CATO-C4X-283679)
- Alectinib Impurity 51 (CAS CATO-C4X-283651)
- Alectinib Impurity 80 (CAS CATO-C4X-283680)
- Alectinib Impurity 84 (CAS CATO-C4X-283684)
- Alectinib impurity 26 (CAS CATO-C4X-283626)
- Alectinib Impurity 57 (CAS CATO-C4X-283657)
Recommended Standards
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