Glutamic acid impurity 9 CAS CATO-C4X-28629
| CAS No. | CATO-C4X-28629 |
| Molecular Formula | C8H10F3NO5 |
| Molecular Weight | 257.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Glutamic acid impurity 9 is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Glutamic acid impurity 9 (CAS CATO-C4X-28629), a pharmacopoeial impurity reference standard (molecular formula C8H10F3NO5, MW 257.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Glutamic acid impurity 9 (C8H10F3NO5) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 257.16 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Glutamic acid impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10F3NO5 |
| Molecular Weight | 257.16 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Glutamic Standards
- L-Glutamic Acid Di-tert-butyl Ester (CAS 16874-06-9)
- L-Glutamic acid γ-(2,2,2-trichloroethyl) ester (CAS 92739-23-6)
- L-Glutamic acid γ-(3-carboxy-4-hydroxyanilide) (CAS 74929-17-2)
- Glutamic acid Impurity 4 (CAS 57444-70-9)
- Glutamic acid impurity 5 (CAS 87039-96-1)
- Glutamic acid impurity 6 (CAS 1308957-12-1)
- Glutamic acid impurity 7 (CAS CATO-C4X-28627)
- L-Glutamic acid, 4-(2-naphthalenylmethyl)-, (4R)- (CAS 207497-67-4)
Recommended Standards
- Ethyl 4-(perfluoroethyl)-1H-pyrrole-2-carboxylate (CAS 2180956-75-4)
- 5-[2-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxylic acid (CAS 1003561-80-5)
- Cyclohexyl 3,5-dichlorophenyl ketone (CAS 898769-51-2)
- 1-[5-(trifluoromethyl)pyridin-2-yl]-1h-pyrazole-3-carboxylic acid (CAS 1006962-72-6)
- Indobufen Impurity 38 (CAS CATO-C4X-179238)
- Bromfenac Impurity 34 (CAS CATO-C4X-200234)
- Palbociclib Impurity 107 (CAS CATO-C4X-1125107)
- 9-(Tert-butoxycarbonyl)-9-azabicyclo[3.3.1]Nonane-2-carboxylic acid (CAS 1823776-63-1)
- (E)-N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N'-methyl-2-(4-methylbenzylidene)hydrazine-1-carbohydrazide (CAS 866149-28-2)
- 6-(4-(Trifluoromethyl)phenyl)pyridazin-3-amine (CAS 1215073-83-8)
- Acenaphthylene-d8 (CAS 93951-97-4)
- Tert-butyl (R)-(3-(hydroxymethyl)pyrrolidin-3-yl)carbamate (CAS 1412258-41-3)
- Vanillyl Butyl Ether (CAS 82654-98-6)
- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com