Abrocitinib Impurity 2 CAS CATO-C4X-28842
| CAS No. | CATO-C4X-28842 |
| Molecular Formula | C14H21N5O3S |
| Molecular Weight | 339.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Abrocitinib Impurity 2 (CAS CATO-C4X-28842) is a certified pharmaceutical impurity reference standard with the molecular formula C14H21N5O3S and a molecular weight of 339.41 g/mol.
Structurally, Abrocitinib Impurity 2 (C14H21N5O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 339.41 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Abrocitinib Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H21N5O3S |
| Molecular Weight | 339.41 g/mol |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Abrocitinib Standards
- Abrocitinib Impurity 1 (CAS CATO-C4X-28841)
- Abrocitinib Impurity 20 (CAS CATO-C4X-288420)
- Abrocitinib Impurity 32 (CAS CATO-C4X-288432)
- Abrocitinib Impurity 50 (CAS CATO-C4X-288450)
- Abrocitinib Impurity 25 (CAS 2744171-52-4)
- Abrocitinib Impurity 26 (CAS 2744171-53-5)
- Abrocitinib Impurity 41 (CAS 2504210-45-9)
- Abrocitinib Impurity 12 (CAS CATO-C4X-288412)
Recommended Standards
- Hydroxy Gliclazide (CAS 87368-00-1)
- Amoxicillin EP Impurity E-2 (CAS CATO-C4X-114873)
- N-Oxide Abrocitinib Impurity 33 (CAS CATO-C4X-288433)
- Amoxicillin EP Impurity E-1 (CAS CATO-C4X-114872)
- Talazoparib Impurity N57 (CAS 1425767-92-5)
- Dotinurad Impurity 20 (CAS CATO-C4X-249420)
- Procaterol Impurity 27 (CAS CATO-C4X-181027)
- (S)-3-(amino(cyclopropyl)methyl)benzonitrile hydrochloride (CAS 1391436-28-4)
- (S)-4-(3-Phosphonopropyl)piperazine-2-carboxylic acid (CAS 124190-29-0)
- 4-Oxaspiro[bicyclo[3.2.0]heptane-6,1'-cyclobutane]-7-ol (CAS 1423028-41-4)
- 2-phenylquinolin-4-ol (CAS 1144-20-3)
- N-Methyl Viloxazine (CAS 48173-47-3)
- 3-Amino-n,n-diethyl-5-methylisoxazole-4-sulfonamide (CAS 1354536-19-8)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com