Pibrentasvir Impurity 1 CAS CATO-C4X-28931
| CAS No. | CATO-C4X-28931 |
| Molecular Formula | C57H65F5N10O8 |
| Molecular Weight | 1113.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pibrentasvir Impurity 1.
As a process- or degradation-related impurity, Pibrentasvir Impurity 1 (CAS CATO-C4X-28931, C57H65F5N10O8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Pibrentasvir Impurity 1 (C57H65F5N10O8) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Pibrentasvir Impurity 1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C57H65F5N10O8 |
| Molecular Weight | 1113.18 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 28.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 10 |
Related Pibrentasvir Standards
- Pibrentasvir (CAS 1353900-92-1)
- Pibrentasvir impurity 3 (CAS CATO-C4X-28933)
- Pibrentasvir impurity 4 (CAS CATO-C4X-28934)
- Pibrentasvir impurity 2 (CAS CATO-C4X-28932)
- Pibrentasvir impurity 6 (CAS CATO-C4X-28936)
- Pibrentasvir impurity 5 (CAS CATO-C4X-28935)
- Pibrentasvir Impurity 4 (CAS 1292836-20-4)
- Pibrentasvir Impurity 3 (CAS 1332356-31-6)
Recommended Standards
- Relugolix Impurity 177 (CAS CATO-C4X-2429177)
- Des-1,2-diglycine-Terlipressin (CAS 4235-50-1)
- Ruilugoli lmpurity 126 (CAS CATO-C4X-2429126)
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- Vinorelbine EP Impurity J (CAS 38390-45-3)
- Isoprenaline Impurity 17 (CAS CATO-C4X-277517)
- Dexmedetomidine Impurity 87 (CAS CATO-C4X-123087)
- 4-(2-(Piperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl)thiomorpholine 1-oxide dihydrochloride (CAS 39547-34-7)
- 2-Methoxy-1-ethanesulfonyl Chloride (CAS 51517-01-2)
- Methyl 5-(4-fluorobenzoyl)furan-2-carboxylate (CAS 170632-16-3)
- (2E)-N-[(4-Fluorophenyl)methyl]-3-(4-methoxynaphthalen-1-yl)prop-2-enamide (CAS 882079-68-7)
- 3-Phenyldibenzothiophene (CAS 98251-30-0)
- CID 71750944 (CAS 1329834-19-6)
- Tau Peptide (512-525) amide trifluoroacetate salt (CAS 2022956-61-0)
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