Letermovir Impurity 12 CAS CATO-C4X-291512
| CAS No. | CATO-C4X-291512 |
| Molecular Formula | C20H18F4N2O4 |
| Molecular Weight | 426.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Letermovir Impurity 12 (CAS CATO-C4X-291512), a pharmacopoeial impurity reference standard (molecular formula C20H18F4N2O4, MW 426.36 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C20H18F4N2O4, Letermovir Impurity 12 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 426.36 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Letermovir Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H18F4N2O4 |
| Molecular Weight | 426.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Letermovir Standards
- Letermovir impurity 129 (CAS 917389-18-5)
- Letermovir Impurity 25 (CAS CATO-C4X-291525)
- Letermovir impurity 122 (CAS CATO-C4X-2915122)
- Letermovir impound 123 (CAS CATO-C4X-2915123)
- Letermovir Impurity 3 (CAS CATO-C4X-29153)
- Letermovir Impurity 22 (CAS CATO-C4X-291522)
- Letermovir impurity 137 (CAS CATO-C4X-2915137)
- Letermovir Impurity 58 (CAS CATO-C4X-291558)
Recommended Standards
- Methyl 4-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-((2-(trimethylsilyl)ethoxy)methoxy)benzoate (CAS 2787516-03-2)
- (2R,3R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate (CAS 108907-43-3)
- 7-(4-Phenylpiperazin-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 241488-25-5)
- (R)-5-(5-Amino-3,3-difluoropiperidin-1-yl)-N-(3-(difluoromethyl)-1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 1710554-33-8)
- Polaprezinc Impurity 35 DiHCI (CAS 46119-06-6（free base）)
- Methylnaltrexone Bromide Impurity 2 (CAS CATO-C4X-15212)
- Diquafosol Impurity 12 (CAS 19817-92-6)
- 2-(2-(Quinolin-8-ylmethylene)hydrazinyl)benzoic acid (CAS 61910-23-4)
- 4-(phenylsulfonyl)-3-propyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 1009526-41-3)
- (5S,6E,8Z,10Z,14Z)-5-Hydroxy-12-oxoicosa-6,8,10,14-tetraenoic acid (CAS 136696-10-1)
- 3-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1-(3-chlorobenzyl)-1H-pyrazole (CAS 477711-61-8)
- Levothyroxine Impurity 27 (CAS 671235-41-9)
- Benzyl spiro[indoline-3,4'-piperidine]-1-carboxylate (CAS 167483-91-2)
- Des-Tyr10-Tirzepatide (CAS CATO-CPTD788680)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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