Letermovir impurity 128 CAS CATO-C4X-2915128
| CAS No. | CATO-C4X-2915128 |
| Molecular Formula | C29H28F4N4O5 |
| Molecular Weight | 588.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Letermovir impurity 128 (CAS CATO-C4X-2915128) is a certified pharmaceutical impurity reference standard with the molecular formula C29H28F4N4O5 and a molecular weight of 588.55 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Letermovir impurity 128 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 588.55 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Letermovir impurity 128 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H28F4N4O5 |
| Molecular Weight | 588.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Letermovir Standards
- Letermovir Impurity 27 (CAS 2991059-71-1)
- Letermovir impurity 55 (CAS CATO-C4X-291555)
- Letermovir Impurity N19 (CAS 791117-40-3)
- Letermovir Impurity 1 (CAS 917389-29-8)
- Letermovir Impurity 100 (CAS CATO-C4X-2915100)
- Letermovir impurity 136 (CAS CATO-C4X-2915136)
- Letermovir Impurity 59 (CAS CATO-C4X-291559)
- Letermovir Impurity 87 (CAS CATO-C4X-291587)
Recommended Standards
- 3-[2-Fluoro-6-(trifluoromethyl)phenyl]-1-{1-[2-(2-methylphenyl)-2-oxoethyl]-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl}urea (CAS 1796929-68-4)
- Dibromobis(3-amino-2H-1-benzopyran-2-one-N)palladium (CAS 76295-01-7)
- CEP-40783 (CAS 1437321-24-8)
- Antrafenine - API Standards (CAS 55300-29-3)
- Pregnenolone Impurity 11 (CAS 6795-58-0)
- Pramipexole Impurity BI-IO460BS (CAS 1246833-75-9)
- Melatonin Impurity N1 (CAS 109210-52-8)
- Methyl 4-(4-cyanopyridin-2-yl)benzoate (CAS 886361-52-0)
- 3-(5-Chloro-7H-pyrrolo[2,3-b]pyridin-6-yl)propan-1-ol (CAS 1305325-26-1)
- 3-Methoxy-4-(morpholinosulfonyl)aniline (CAS 436091-52-0)
- (8-Methoxyquinolin-3-yl)methanamine (CAS 1267869-19-1)
- 5-Chloro-3-cyclobutyl-1,2,4-oxadiazole (CAS 1188264-96-1)
- 2-(1-Benzyl-4-methyl-3-oxo-2-piperazinyl)-acetic acid (CAS 1236267-76-7)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
Why CATO?
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