Letermovir Impurity 1 CAS 917389-29-8
| CAS No. | 917389-29-8 |
| Molecular Formula | C30H30F4N4O4 |
| Molecular Weight | 586.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Letermovir Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Letermovir Impurity 1 (CAS 917389-29-8, C30H30F4N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Letermovir Impurity 1 (C30H30F4N4O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C30H30F4N4O4 |
| Molecular Weight | 586.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Letermovir Standards
- Letermovir Impurity N19 (CAS 791117-40-3)
- Letermovir Impurity 100 (CAS CATO-C4X-2915100)
- Letermovir impurity 136 (CAS CATO-C4X-2915136)
- Letermovir Impurity 59 (CAS CATO-C4X-291559)
- Letermovir Impurity 87 (CAS CATO-C4X-291587)
- Letermovir Impurity 96 (CAS CATO-C4X-291596)
- Letermovir impurity 57 (CAS CATO-C4X-291557)
- Letermovir impurity 128 (CAS CATO-C4X-2915128)
Recommended Standards
- Osimertinib impurity 58 (CAS CATO-C4X-204558)
- Ceftriaxone Impurity 25 (CAS CATO-C4X-116325)
- N-((5-((2-(Benzo[d]thiazol-2-ylamino)-2-oxoethyl)thio)-4-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-yl)methyl)-2-fluorobenzamide (CAS 391899-60-8)
- Methyl (R)-2-(8-fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetate (CAS 917389-34-5)
- Nebivolol Impurity 9 (CAS CATO-C4X-19689)
- Salbutamol Glyoxal Impurity (CAS 72189-44-7)
- Mosapride Impurity 68 (CAS CATO-C4X-104468)
- Pentyl Cyclopentanecarboxylate (CAS 959026-72-3)
- 2-(Difluoromethoxy)isonicotinic Acid (CAS 1211581-51-9)
- 4-Chloro-2-(((3-(trifluoromethoxy)phenyl)amino)methyl)phenol (CAS 1041573-47-0)
- 4-(P-tolylthio)cyclohexan-1-amine (CAS 1342063-21-1)
- 3-(Boc-amino)-4-(4-methylphenyl)butyric Acid (CAS 683219-72-9)
- 5-Bromo-2-fluoro-3-(morpholine-4-sulfonyl)benzoic acid (CAS 926189-44-8)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com