Letermovir impurity 57 CAS CATO-C4X-291557
| CAS No. | CATO-C4X-291557 |
| Molecular Formula | C27H22F7N3O4 |
| Molecular Weight | 585.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 585.47 g/mol gives Letermovir impurity 57 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Letermovir impurity 57 (CAS CATO-C4X-291557) is a certified pharmaceutical impurity reference standard with the molecular formula C27H22F7N3O4 and a molecular weight of 585.47 g/mol.
The molecular framework of Letermovir impurity 57 (C27H22F7N3O4) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H22F7N3O4 |
| Molecular Weight | 585.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Letermovir Standards
- Letermovir Impurity 89 (CAS CATO-C4X-291589)
- Letermovir Impurity 106 (CAS CATO-C4X-2915106)
- Letermovir Impurity N19 (CAS 791117-40-3)
- Letermovir Impurity 1 (CAS 917389-29-8)
- Letermovir Impurity 100 (CAS CATO-C4X-2915100)
- Letermovir impurity 136 (CAS CATO-C4X-2915136)
- Letermovir Impurity 59 (CAS CATO-C4X-291559)
- Letermovir Impurity 87 (CAS CATO-C4X-291587)
Recommended Standards
- 931212-77-0 N,N'-[Sulfonylbis(4,1-phenyleneoxy-4,1-phenylene)]bis(2-chloroacetamide) MFCD09598050 (CAS 931212-77-0)
- Suvorexant Impurity 47 (CAS CATO-C4X-181247)
- Chlorophenol red β-D-galactopyranoside (CAS 99792-79-7)
- Florfenicol Impurity 13 (CAS CATO-C4X-207513)
- Resmetirom impurity 68 (CAS CATO-C4X-291268)
- Crizotinib impurity 19 (CAS CATO-C4X-102519)
- Alogliptin Impurity 62 (CAS 607376-86-3)
- Prasugrel Impurity 36 (CAS 866761-69-5)
- 5-Chloro-1-methyl-3,4-bis((p-tolylthio)methyl)-1H-pyrazole (CAS 318248-69-0)
- 2-(2,6-dioxo-3-piperidyl)-4-(4-hydroxybutyl)isoindoline-1,3-dione (CAS 2503018-10-6)
- 2-(5-((1H-1,2,4-triazol-1-yl)methyl)-1H-1,2,4-triazol-3-yl)acetonitrile (CAS 477852-49-6)
- 3-Chloro-1H-pyrrolo[3,2-b]pyridin-6-ol (CAS 1190316-89-2)
- 2-((4-Isobutyl-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-2-yl)thio)acetic acid (CAS 1242960-73-1)
- Des-Lys16-Tirzepatide (CAS CATO-CPTD788957)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com