Abemaciclib Impurity 36 CAS CATO-C4X-293736
| CAS No. | CATO-C4X-293736 |
| Molecular Formula | C10H13F2NO |
| Molecular Weight | 201.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 201.21 g/mol gives Abemaciclib Impurity 36 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Abemaciclib Impurity 36 (CAS CATO-C4X-293736) is a certified pharmaceutical impurity reference standard with the molecular formula C10H13F2NO and a molecular weight of 201.21 g/mol.
Based on its molecular formula C10H13F2NO, Abemaciclib Impurity 36 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 201.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Abemaciclib Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13F2NO |
| Molecular Weight | 201.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Abemaciclib Standards
- Abemaciclib Impurity 7 (CAS 414881-11-1)
- Abemaciclib Impurity 61 (CAS 827587-92-8)
- Abemaciclib Impurity 1 (CAS CATO-C4X-29371)
- Abemaciclib Impurity 181 (CAS CATO-C4X-2937181)
- Abemaciclib Impurity 2 (CAS 1528469-78-4)
- Abemaciclib impurity 117 (CAS CATO-C4X-2937117)
- Abemaciclib Impurity 76 (CAS CATO-C4X-293776)
- Abemaciclib Impurity 53 (CAS CATO-C4X-293753)
Recommended Standards
- 4-(tert-butoxy)-3,5-difluoroaniline (CAS 942615-17-0)
- (2-Methyl-quinolin-6-yl)-acetic acid (CAS 1000542-76-6)
- 2-Butoxy-3,4-difluoroaniline (CAS 935251-05-1)
- 2-Hydroxy-2-phenyl-1-(1H-pyrrol-2-yl)ethanone (CAS 100063-06-7)
- Flupentixol Impurity N42 (CAS 28973-34-4)
- Telmisartan Impurity 92 (CAS CATO-C4X-135992)
- Gadoxetate impurity 21 (CAS CATO-C4X-261821)
- 2-Chloro-3,6-dimethyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one (CAS 2102325-48-2)
- 1-Isobutyl-2-(2-methoxyphenyl)piperidine (CAS 1355181-46-2)
- 2-(4-Amino-3-nitrophenoxy)ethan-1-ol (CAS 50982-74-6)
- 6-Chloro-5-(difluoromethyl)-3-methoxypyridin-2-ol (CAS 1807075-30-4)
- 1-(5-Chloro-2,4-dimethoxyphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 793727-58-9)
- 2-Methoxyethyl 7-(3,4-dimethoxyphenyl)-4-(3-hydroxyphenyl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 493002-68-9)
- (Leu31,Pro3?)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 125580-28-1)
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