Abemaciclib Impurity 76 CAS CATO-C4X-293776

Description

Compared with other compounds in its class, the molecular weight of 212.24 g/mol gives Abemaciclib Impurity 76 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Abemaciclib Impurity 76 (CAS CATO-C4X-293776) is a certified pharmaceutical impurity reference standard with the molecular formula C11H14F2N2 and a molecular weight of 212.24 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, Abemaciclib Impurity 76 is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 212.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Abemaciclib Impurity 76 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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