Eravacycline impurity 37 CAS CATO-C4X-293837
| CAS No. | CATO-C4X-293837 |
| Molecular Formula | C21H20FN3O6 |
| Molecular Weight | 429.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 429.40 g/mol gives Eravacycline impurity 37 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Eravacycline impurity 37 (CAS CATO-C4X-293837) is a certified pharmaceutical impurity reference standard with the molecular formula C21H20FN3O6 and a molecular weight of 429.40 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Eravacycline impurity 37 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 429.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Eravacycline impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H20FN3O6 |
| Molecular Weight | 429.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Eravacycline Standards
- Eravacycline impurity 41 (CAS CATO-C4X-293841)
- Eravacycline Impurity 10 (CAS 1207283-60-0)
- Eravacycline impurity 17 (CAS 1431558-62-1)
- Eravacycline impurity 29 (CAS CATO-C4X-293829)
- Eravacycline impurity 18 (CAS CATO-C4X-293818)
- Eravacycline impurity 28 (CAS CATO-C4X-293828)
- Eravacycline impurity 38 (CAS CATO-C4X-293838)
- Eravacycline Impurity 12(TP-5799） (CAS CATO-C4X-293812)
Recommended Standards
- Sulfamethoxazole b-D-Glucuronide (CAS 14365-52-7)
- 6-(Methoxymethoxy)-2-(((3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole (CAS 1184993-29-0)
- (2R,3R,4R,5R)-2-(4-((Butoxycarbonyl)amino)-5-fluoro-2-oxopyrimidin-1(2H)-yl)-5-methyltetrahydrofuran-3,4-diyl diacetate (CAS 162204-19-5)
- 3,7-Dichloro-5,5-dimethyl-5H-dibenzo[b,f]silepine (CAS 1278522-47-6)
- Melphalan Impurity 28 (CAS CATO-C4X-198828)
- Osimertinib Impurity 82 (CAS CATO-C4X-204582)
- Milnacipran impound 35 (CAS 105310-24-5)
- 1-Naphthylacetic Acid 4-Nitrophenyl Ester (CAS 51537-87-2)
- 5-Methyl-1-(piperidin-4-yl)-1H-benzo[d][1,2,3]triazole dihydrochloride (CAS 2034154-83-9)
- Ethyl 6-(phenylcarbamoyl)-4-(trifluoromethyl)pyridine-2-carboxylate (CAS 1210182-96-9)
- Irinotecan Impurity 59 (CAS CATO-C4X-166759)
- 4-(5-Methylthiophen-2-yl)butan-2-amine (CAS 303070-17-9)
- 1-(Oxolane-2-carbonyl)-1,4-diazepane (CAS 63035-27-8)
- Semaglutide impurity 270 (CAS CATO-C4X-2226270)
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