Irinotecan Impurity 59 CAS CATO-C4X-166759
| CAS No. | CATO-C4X-166759 |
| Molecular Formula | C21H38N4O |
| Molecular Weight | 362.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Irinotecan Impurity 59 (CAS CATO-C4X-166759) is a certified pharmaceutical impurity reference standard with the molecular formula C21H38N4O and a molecular weight of 362.55 g/mol.
The molecular framework of Irinotecan Impurity 59 (C21H38N4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H38N4O |
| Molecular Weight | 362.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Irinotecan Standards
- Irinotecan Hydrochloride Trihydrate EP Impurity B (CAS 19685-09-7)
- Irinotecan Impurity 9 (CAS 80758-83-4)
- Irinotecan EP Impurity F (CAS 78287-27-1)
- Irinotecan Impurity 23 (CAS 1217633-65-2)
- Irinotecan Impurity 8 (CAS 78287-14-6)
- Irinotecan Impurity 56 (CAS 797762-11-9)
- Irinotecan Impurity 49 (CAS 177611-40-4)
- Irinotecan Impurity 70 (CAS 100286-91-7)
Recommended Standards
- Octyl 3,5-di-tert-butyl-4-hydroxybenzoate (CAS 66130-81-2)
- Teprenone impurity 45 (CAS CATO-C4X-208145)
- 4-Hydroxybenzoic acid hexadecylester (CAS 71067-09-9)
- Teprenone impurity 48 (CAS CATO-C4X-208148)
- Lifitegrast Impurity 172 (CAS CATO-C4X-2409172)
- Ivabradine impurity 84 (CAS 869856-10-0)
- Loxoprofen Impurity 168 (CAS CATO-C4X-1488168)
- Tert-butyl (1S,4S)-6-amino-2-azabicyclo[2.2.1]Heptane-2-carboxylate (CAS 1933764-12-5)
- 1-Ethyl-1H,4H,5H,6H,7H-imidazo[4,5-c]pyridine (CAS 912259-16-6)
- (R)-2-(6-Fluoro-1H-benzo[d]imidazol-1-yl)-9-(8-fluorochroman-4-yl)-7H-purin-8(9H)-one (CAS 911824-55-0)
- 1-(2-Chloro-7-(pentan-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)ethanone (CAS 959799-20-3)
- 8-methyl-1H,4H-pyrazolo[1,5-a][1,3,5]triazin-4-one (CAS 77668-03-2)
- 1-((2R,3R,4R,5R)-3-Bromo-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione (CAS 95585-76-5)
- Semaglutide impurity 101 (CAS CATO-C4X-2226101)
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