Linzagolix Impurity 4 CAS CATO-C4X-29414
| CAS No. | CATO-C4X-29414 |
| Molecular Formula | C12H16FNO4 |
| Molecular Weight | 257.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Linzagolix Impurity 4.
As a process- or degradation-related impurity, Linzagolix Impurity 4 (CAS CATO-C4X-29414, C12H16FNO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Linzagolix Impurity 4 (C12H16FNO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 257.26 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16FNO4 |
| Molecular Weight | 257.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Linzagolix Standards
Recommended Standards
- Delamanid Impurity 2 (CAS CATO-C4X-25142)
- Carmofur (CAS 61422-45-5)
- Safinamide Impurity 63 (CAS CATO-C4X-159063)
- 3-(1,3-Benzothiazol-2-yl)pyrazine-2-carboxylic acid (CAS 100283-52-1)
- Esmolol Impurity 74 (CAS CATO-C4X-189174)
- Cefaclor EP Impurity A Hydrochloride (CAS 25705-52-6)
- Nemonoxacin Impurity 99 (CAS CATO-C4X-312899)
- 2-Chloro-3-(4-(methylsulfonyl)piperazin-1-yl)pyrazine (CAS 1281400-85-8)
- (-)-Linalool(Mixture of enantiomers) (CAS 126-91-0)
- 4-(Hexylthio)-2-(4-methylpiperazin-1-yl)quinazoline maleate (CAS 129664-15-9)
- (3R,8AR)-3-methylhexahydropyrrolo[1,2-a]pyrazin-4(1H)-one hydrochloride (CAS 2230901-06-9)
- 2-Amino-2-ethylhexanoic acid (CAS 114781-15-6)
- 3-nitro-1H-pyrazolo[3,4-b]pyridine (CAS 116855-00-6)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
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