Cefaclor EP Impurity A Hydrochloride CAS 25705-52-6
| CAS No. | 25705-52-6 |
| Molecular Formula | C8H9NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 187.62 g/mol gives Cefaclor EP Impurity A Hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Cefaclor EP Impurity A Hydrochloride (CAS 25705-52-6), a pharmacopoeial impurity reference standard (molecular formula C8H9NO2HCl, MW 187.62 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C8H9NO2HCl, Cefaclor EP Impurity A Hydrochloride contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 187.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cefaclor EP Impurity A Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9NO2 HCl |
| Molecular Weight | 187.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1964 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Cefaclor Standards
- Cefaclor Impurity C10 (CAS 108260-07-7)
- Cefaclor Impurity 46 (CAS 134624-91-2&6453-64-1 (mixture))
- Cefaclor Impurity 23 (CAS 1426173-90-1)
- Cefaclor Impurity 24 (CAS 142975-51-7)
- Cefaclor EP Impurity C (CAS 143059-69-2)
- Cefaclor EP Impurity D (Mixture of Diastereomers) (CAS 152575-13-8)
- Cefaclor EP Impurity E (CAS 188915-50-6)
- Cefaclor Impurity 37 (CAS 21746-02-1)
Recommended Standards
- Pemafibrate Impurity 43 (CAS CATO-C4X-290343)
- Memantine Impurity N2 (CAS 15210-64-7)
- Amisulpride impurity 51 (CAS CATO-C4X-104551)
- 1-methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-2-one hydrochloride (CAS 1955498-88-0)
- (2s,3s)-2-Amino-3-methyl-N-((R)-1-phenylethyl)pentanamide (CAS 156924-94-6)
- N-(4-hydroxy-6-methylpyrimidin-2-yl)-3,4-dihydroquinoline-1(2H)-carboximidamide (CAS 1306753-50-3)
- 1-(1,4-dimethylpiperazin-2-yl)ethan-1-one (CAS 54969-37-8)
- 2-Amino-4,5-dimethoxybenzenethiol (CAS 100601-30-7)
- (R)-2-((tert-butoxycarbonyl)amino)-3-(2-hydroxyphenyl)propanoic acid (CAS 1213668-39-3)
- GnRH Associated Peptide (GAP) (1-13), human (CAS 100111-07-7)
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