Lodoxamide Impurity 20 CAS CATO-C4X-294920
| CAS No. | CATO-C4X-294920 |
| Molecular Formula | C11H6ClN3O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Lodoxamide Impurity 20 (CAS CATO-C4X-294920), a pharmacopoeial impurity reference standard (molecular formula C11H6ClN3O6C4H11NO3, MW 432.77 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Lodoxamide Impurity 20 (C11H6ClN3O6C4H11NO3) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H6ClN3O6 C4H11NO3 |
| Molecular Weight | 432.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Lodoxamide Standards
Recommended Standards
- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
- Rupatadine impurity 11 (CAS CATO-C4X-102711)
- Pazufloxacin Impurity 23 (CAS CATO-C4X-233223)
- 1-(1,3-thiazol-5-yl)ethan-1-one (CAS 91516-28-8)
- 4-(2-Amino-2-oxoethoxy)-3-ethoxybenzoic acid (CAS 869948-80-1)
- 2-(4-Methoxy-3-methylphenyl)butan-2-ol (CAS 1379337-63-9)
- Benzyl (3-chloro-3-oxopropyl)carbamate (CAS 51513-97-4)
- 6-(2-Ethoxyphenoxy)pyridazin-3-amine (CAS 121041-43-8)
- 2,2,4,5-Tetramethyl-1,3-dioxolane-4-carboxylic acid (CAS 57672-01-2)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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