N-Nitroso Metolazone CAS CATO-C4X-29701
| CAS No. | CATO-C4X-29701 |
| Molecular Formula | C16H15ClN4O4S |
| Molecular Weight | 394.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-Nitroso Metolazone.
N-Nitroso Metolazone (CAS CATO-C4X-29701), molecular formula C16H15ClN4O4S and molecular weight 394.83 g/mol, is a CATO reference standard with documented purity and traceability.
N-Nitroso Metolazone (C16H15ClN4O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-Nitroso Metolazone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H15ClN4O4S |
| Molecular Weight | 394.83 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related N Standards
- N-Nitroso Indapamide (CAS CATO-C4X-140044)
- N-Nitroso N-Devaleryl Valsartan Methyl Ester Impurity 89 (mixture of isomers) (CAS CATO-C4X-105789)
- N-Nitroso Amoxicillin EP Impurity C (CAS CATO-C4X-114876)
- N-Nitroso Amoxicillin Impurity 98 (CAS CATO-C4X-114898)
- N1-Nitroso Rilpivirine (CAS CATO-C4X-13638)
- N2-Nitroso Rolapitant (CAS CATO-C4X-13639)
- N-Nitroso Indacaterol Mono Ethyl Impurity 65 (CAS CATO-C4X-150065)
- N-Nitroso Bumetanide (CAS 2490432-02-3)
Recommended Standards
- Metolazone impurity 2 (CAS CATO-C4X-29702)
- 2-Chloro-4-(1-(phenylsulfonyl)-1H-indol-3-yl)pyrimidine-5-carbonitrile (CAS 2306272-87-5)
- 2,4-Dimethyl-9H-carbazole (CAS 18992-71-7)
- 2-(4-Chloro-2-methylphenoxy)-N-{[(4-nitrophenyl)carbamothioyl]amino}acetamide (CAS 708220-95-5)
- 1-(1-Methyl-1h-pyrazol-4-yl)propan-2-one (CAS 1250912-51-6)
- 2,6-Difluorobenzylisocyanide (CAS 730964-51-9)
- 4-[(3,5-Dimethoxybenzyl)oxy]piperidinehydrochloride (CAS 1220036-75-8)
- (2R)-2-(((2R)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)propan-2-yl)oxy)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethyl benzoate (CAS 1120329-48-7)
- 4-(2,5-Dimethyl-phenyl)-2H-phthalazin-1-one (CAS 93517-76-1)
- 6-Ethoxy-N-(furan-2-ylmethyl)benzo[d]thiazol-2-amine (CAS 1286732-80-6)
- Tert-butyl 2-methyl-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate (CAS 1427021-80-4)
- [1-(6-Ethoxy-pyrimidin-4-yl)-piperidin-3-yl]-methyl-carbamic acid tert-butyl ester (CAS 1353984-21-0)
- 2-(Hydrazinecarbonyl)-N-methyl-4-phenyl-N-(p-tolyl)thiophene-3-sulfonamide (CAS 931965-73-0)
- Semaglutide Impurity 180 (CAS CATO-C4X-2226180)
Why CATO?
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