Mefatinib Impurity 19 CAS CATO-C4X-299219
| CAS No. | CATO-C4X-299219 |
| Molecular Formula | C15H10ClF3N4O |
| Molecular Weight | 354.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Mefatinib Impurity 19 (C15H10ClF3N4O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Mefatinib Impurity 19 (CAS CATO-C4X-299219) is a certified pharmaceutical impurity reference standard with the molecular formula C15H10ClF3N4O and a molecular weight of 354.71 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10ClF3N4O |
| Molecular Weight | 354.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Mefatinib Standards
- Mefatinib Impurity 13 (CAS CATO-C4X-299213)
- Mefatinib Impurity 9 (CAS CATO-C4X-29929)
- Mefatinib Impurity 8 (CAS CATO-C4X-29928)
- Mefatinib Impurity 11 (CAS CATO-C4X-299211)
- Mefatinib Impurity 10 (CAS CATO-C4X-299210)
- Mefatinib Impurity 12 (CAS CATO-C4X-299212)
- Mefatinib Impurity 14 (CAS CATO-C4X-299214)
- Mefatinib Impurity 6 (CAS 1417695-76-1)
Recommended Standards
- 353258-51-2 8-chloro-N-(2-pyridinylmethyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxamide KS-000030FV (CAS 353258-51-2)
- 2-(4-Chlorophenyl)-6-(pentafluoro-λ6-sulfanyl)-1H-benzo[d]imidazole (CAS 1379803-56-1)
- N1-[2-(4-cyanophenoxy)-5-(trifluoromethyl)phenyl]-2-chloroacetamide (CAS 218157-69-8)
- (5-((4-Chlorophenyl)sulfonyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methanol (CAS 318469-34-0)
- Pranoprofen Impurity 29 (CAS CATO-C4X-181129)
- Tirofiban Impurity 45 (CAS 3728-20-9)
- Telmisartan Impurity 57 (CAS 884330-16-9)
- Benzyl (S)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride (CAS 2044704-52-9)
- 5662-75-9 6-phosphonohexanoic Acid DTXSID50448397 (CAS 5662-75-9)
- Lifitegrast Impurity 156 (CAS CATO-C4X-2409156)
- Potassium 2-((phosphonomethyl)amino)acetate (CAS 39600-42-5)
- 4-(2-Aminoethoxy)-N-propylbenzamide (CAS 1018250-85-5)
- benzyl 4-((tert-butoxycarbonyl)amino)-3-fluoropiperidine-1-carboxylate (CAS 1820676-07-0)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com