Bromphenamine Impurity 2 CAS CATO-C4X-29982
| CAS No. | CATO-C4X-29982 |
| Molecular Formula | C16H19BrN2O2 |
| Molecular Weight | 351.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Bromphenamine Impurity 2 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Bromphenamine Impurity 2 (CAS CATO-C4X-29982, C16H19BrN2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Bromphenamine Impurity 2 (C16H19BrN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 351.24 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Bromphenamine Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H19BrN2O2 |
| Molecular Weight | 351.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromphenamine Standards
Recommended Standards
- Ozenoxacin Impurity 51 (CAS CATO-C4X-279651)
- 3-Chloro-N-(2-chloro-5-(pyrrolidin-1-ylsulfonyl)phenyl)propanamide (CAS 1087784-08-4)
- (E,Z)-1-Bromo-1,2-diphenyl-2-(4-hydroxyphenyl)ethene 4-(2-Bromo-1,2-diphenylethenyl)phenol 874504-11-7 |A'-Bromo-|A-phenyl-4-stilbenol (CAS 874504-11-7)
- 5-(2-(2,6-Dichlorobenzyl)pyrimidin-4-yl)-4-methylthiazol-2-amine (CAS 1163706-69-1)
- Papaverine EP Impurity D (Papaveraldine) (CAS 522-57-6)
- Ticagrelor impurity 22 (CAS 1459719-81-3)
- Pidotimod Impurity 26 (CAS CATO-C4X-107826)
- Thiamine Impurity 2 (CAS 3505-34-8)
- 2-(((1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)amino)ethane-1-sulfonic acid (CAS 497258-53-4)
- 5-Bromo-2',3',5'-tri-O-acetyluridine (CAS 105659-32-3)
- 1-Propylindolin-2-one (CAS 15379-41-6)
- NHS SS Biotin (CAS 142439-92-7)
- tert-Butyl (3-(hydroxymethyl)bicyclo[1.1.1]pentan-1-yl)carbamate (CAS 1638765-26-0)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
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