Maribavir Impurity 28 CAS CATO-C4X-300728
| CAS No. | CATO-C4X-300728 |
| Molecular Formula | C11H10Br2Cl2N2O |
| Molecular Weight | 416.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Maribavir Impurity 28 (CAS CATO-C4X-300728, C11H10Br2Cl2N2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Maribavir Impurity 28 (C11H10Br2Cl2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10Br2Cl2N2O |
| Molecular Weight | 416.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Maribavir Standards
- Maribavir Impurity 29 (CAS CATO-C4X-300729)
- Maribavir Impurity 2 (CAS CATO-C4X-30072)
- Maribavir Impurity 15 (CAS 176161-19-6)
- Maribavir Impurity 33 (CAS CATO-C4X-300733)
- Maribavir Impurity 14 (CAS 142356-76-1)
- Maribavir Impurity 31 (CAS CATO-C4X-300731)
- Maribavir-d7 (CAS CATO-C4X-30077)
- Maribavir Impurity 24 (CAS CATO-C4X-300724)
Recommended Standards
- Ziprasidone Impurity 62 (CAS CATO-C4X-124062)
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- Tetrakis[(trimethylsilyl)ethynyl]silane (CAS 13888-92-1)
- Sacubitril impurity 54 (CAS 149709-63-7)
- Cyclophosphamide Impurity 42 (CAS 2387771-96-0)
- Vardenafil Impurity 30 (CAS 1339092-18-0)
- 4-Fluoro-N-(2-(pyridin-4-yl)pyrimidin-4-yl)benzamide (CAS 478039-93-9)
- 4,7-Dihydro-1H-indole (CAS 26686-10-2)
- 3-Chloro-2-methoxybenzyl alcohol (CAS 869088-29-9)
- 3-((4-Hydroxybutyl)imino)-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide (CAS 299202-85-0)
- 5-Amino-1-benzyl-N-(4-fluorobenzyl)-1H-1,2,3-triazole-4-carboxamide (CAS 899749-86-1)
- (R)-2,3,4,6,7,11b-hexahydro-1H-pyrazino[2,1-a]isoquinoline dihydrochloride (CAS 5315-02-6)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
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