Dabrafenib Impurity 26 CAS CATO-C4X-303326
| CAS No. | CATO-C4X-303326 |
| Molecular Formula | C20H12F5NO6S2 |
| Molecular Weight | 521.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Dabrafenib Impurity 26 (CAS CATO-C4X-303326, C20H12F5NO6S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Dabrafenib Impurity 26 (C20H12F5NO6S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dabrafenib Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H12F5NO6S2 |
| Molecular Weight | 521.43 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Dabrafenib Standards
- Dabrafenib Impurity 18 (CAS 1622082-84-1)
- Dabrafenib Impurity 30 (CAS CATO-C4X-303330)
- Dabrafenib (CAS 1195765-45-7)
- Dabrafenib Impurity 24 (CAS CATO-C4X-303324)
- Dabrafenib Impurity 40 (CAS CATO-C4X-303340)
- Dabrafenib Impurity 1 (CAS 2017554-98-0)
- Dabrafenib Impurity 13 (CAS CATO-C4X-303313)
- Dabrafenib-D9 (CAS 1423119-98-5)
Recommended Standards
- Mometasone Impurity 42 (CAS CATO-C4X-170442)
- Mometasone Furoate (CAS 83919-23-7)
- Mometasone Impurity 37 (CAS CATO-C4X-170437)
- 1-(Tert-butyldimethylsilyl)-5-(tributylstannyl)-1H-pyrrolo[2,3-b]pyridine (CAS 754214-65-8)
- Pazopanib Impurity 16 (CAS CATO-C4X-172516)
- Exemestane EP Impurity C (CAS 2130745-60-5)
- Pyrimidine Impurity 3 (CAS CATO-C4X-31753)
- Ethyl 2-(2-cyanoacetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate (CAS 544434-08-4)
- Indoxacarb Impurity 3 (CAS 177905-10-1)
- Methyl 3-Fluoro-4-hydroxybenzoate (CAS 403-01-0)
- Adipic acid, bis(2-(2-butoxyethoxy)ethyl) ester (CAS 141-17-3)
- 2-(Propylthio)ethan-1-ol (CAS 22812-90-4)
- 2'-Amino-[1,1'-biphenyl]-3-carboxylic acid hydrochloride (CAS 1172351-47-1)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com