Fruquintinib Impurity 6 CAS CATO-C4X-30376
| CAS No. | CATO-C4X-30376 |
| Molecular Formula | C20H16ClN3O4 |
| Molecular Weight | 397.81 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 397.81 g/mol gives Fruquintinib Impurity 6 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Fruquintinib Impurity 6 (CAS CATO-C4X-30376), a pharmacopoeial impurity reference standard (molecular formula C20H16ClN3O4, MW 397.81 g/mol) used for the identification and quantification of trace impurities in APIs.
Fruquintinib Impurity 6 (C20H16ClN3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Fruquintinib Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H16ClN3O4 |
| Molecular Weight | 397.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Fruquintinib Standards
- Fruquintinib-d6 (CAS 2978508-76-6)
- Fruquintinib Impurity 10 (CAS CATO-C4X-303710)
- Fruquintinib Impurity 8 (CAS CATO-C4X-30378)
- Fruquintinib (CAS 1194506-26-7)
- Fruquintinib Impurity 15 (CAS CATO-C4X-303715)
- Fruquintinib Impurity 5 (CAS CATO-C4X-30375)
- Fruquintinib Impurity 4 (CAS 860749-26-4)
- Fruquintinib impurity 7 (CAS CATO-C4X-30377)
Recommended Standards
- Ethyl 3-(4-chlorobenzamido)-2-oxo-6-phenyl-2H-pyran-5-carboxylate (CAS 338404-92-5)
- 2-(5-(3-Chloro-4-methylphenyl)-4,6-dioxo-4,5,6,6a-tetrahydropyrrolo[3,4-d][1,2,3]triazol-1(3aH)-yl)-N-phenylacetamide (CAS 1009200-90-1)
- Ethyl 3-(3-chlorobenzamido)-2-oxo-6-phenyl-2H-pyran-5-carboxylate (CAS 339009-30-2)
- 3-((3-Chlorophenyl)sulfonyl)-6,7-difluoro-1-propylquinolin-4(1H)-one (CAS 1326860-25-6)
- Posaconazole Impurity 90 (CAS CATO-C4X-1208190)
- Palonosetron Impurity 36 (CAS CATO-C4X-110536)
- Teprenone Impurity 26 (CAS CATO-C4X-208126)
- 4-Methoxy-2-methylquinolin-8-ol (CAS 167834-50-6)
- 5-Chloro-5,6,7,8-tetrahydroquinoline (CAS 198401-82-0)
- 2-oxo-1H,2H,3H-pyrrolo[2,3-b]pyridine-5-carbonitrile (CAS 1190321-76-6)
- 4-Bromo-1-(2-methylpentyl)-1h-pyrazol-3-amine (CAS 1249867-00-2)
- 1,3-Dimethyl-2-(trifluoromethyl)benzene (CAS 41818-96-6)
- 5-Chloro-N-(2-chlorobenzyl)pyrazine-2-carboxamide (CAS 1438853-89-4)
- Endo-Gly4-Semaglutide (CAS CATO-C4X-222679)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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