Niflumic acid impurity 2 CAS CATO-C4X-30852
| CAS No. | CATO-C4X-30852 |
| Molecular Formula | C14H10F3N3O3 |
| Molecular Weight | 325.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Niflumic acid impurity 2 (C14H10F3N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 325.24 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Niflumic acid impurity 2 (CAS CATO-C4X-30852) is a certified pharmaceutical impurity reference standard with the molecular formula C14H10F3N3O3 and a molecular weight of 325.24 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Niflumic acid impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10F3N3O3 |
| Molecular Weight | 325.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Niflumic Standards
Recommended Standards
- Apalutamide impurity 93 (CAS CATO-C4X-274993)
- 8-Benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-8-azabicyclo[3.2.1]oct-3-ene (CAS 1123661-15-3)
- U 4793e (CAS 67579-24-2)
- 5-(1,3-dimethyl-1H-pyrazol-4-yl)-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1171045-38-7)
- Perindopril Impurity 76 (CAS CATO-C4X-125276)
- Epalrestat impurity 32 (CAS CATO-C4X-223632)
- Teneligliptin Impurity 54 (CAS CATO-C4X-176054)
- Ytterbium carbonate hydrate, 99.99% (CAS 5895-52-3)
- 1-bromo-2-iodo-4-methoxy-benzene (CAS 4897-68-1)
- 3-Chloro-N-((6-methoxypyridin-3-yl)methyl)-5-(trifluoromethyl)pyridin-2-amine (CAS 1197904-83-8)
- Vitamin impurity 53 (CAS 286475-07-8)
- Lenvatinib Impurity 118 (CAS CATO-C4X-1140118)
- 5-(2-chloro-4-(trifluoromethyl)phenoxy)-2-nitrophenol 5424-66-8 AR-1G5001 (CAS 5424-66-8)
- Semaglutide impurity 261 (CAS CATO-C4X-2226261)
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