Ribociclib Impurity 28 CAS CATO-C4X-310028
| CAS No. | CATO-C4X-310028 |
| Molecular Formula | C14H18N4O2 |
| Molecular Weight | 274.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ribociclib Impurity 28 (C14H18N4O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Ribociclib Impurity 28 (CAS CATO-C4X-310028) is a certified pharmaceutical impurity reference standard with the molecular formula C14H18N4O2 and a molecular weight of 274.32 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ribociclib Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H18N4O2 |
| Molecular Weight | 274.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Ribociclib Standards
- Ribociclib Impurity 14 (CAS 1331847-17-6)
- Ribociclib Impurity 35 (CAS CATO-C4X-310035)
- Ribociclib impurity 39 (CAS 2304957-86-4)
- Ribociclib Impurity 15 (CAS CATO-C4X-310015)
- Ribociclib Impurity 29 (CAS CATO-C4X-310029)
- Ribociclib Impurity 33 (CAS CATO-C4X-310033)
- Ribociclib Impurity 36 (CAS 2387711-02-4)
- Ribociclib Impurity 22 (CAS CATO-C4X-310022)
Recommended Standards
- Dalilesen impurity 26 (CAS CATO-C4X-301026)
- Ormetoprim (CAS 6981-18-6)
- Melatonin Impurity 30 (CAS 188396-95-4)
- Bisdesoxyquinoceton (CAS 80109-63-3)
- Rocuronium Impurity 12 (CAS 50588-42-6)
- Ticagrelor Impurity 68 Oxalate (CAS CATO-C4X-109368)
- Spironolactone Impurity 20 (CAS CATO-C4X-134520)
- 5-(2-(Piperidin-1-yl)ethyl)-1,3,4-thiadiazol-2-amine (CAS 14069-11-5)
- 2-[2-(1-Methyl-2-piperidinyl)ethoxy]-3-phenylpropylamine (CAS 883531-30-4)
- 1-((4-Nitrobenzyl)amino)propan-2-ol (CAS 893574-11-3)
- 2,2,2-Trifluoro-1-(2'-methoxy-[1,1'-biphenyl]-3-yl)ethan-1-one (CAS 1443332-13-5)
- 2-Methyl-6-(1-tosylpyrrolidin-2-yl)pyridine (CAS 1352533-24-4)
- 2-Bromo-5-iodopyrimidine (CAS 905856-70-4)
- Semaglutide impurity 107 (CAS CATO-C4X-2226107)
Why CATO?
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