Trifarotene impurity 22 CAS CATO-C4X-313222
| CAS No. | CATO-C4X-313222 |
| Molecular Formula | C29H32N2O2 |
| Molecular Weight | 440.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Trifarotene impurity 22 (C29H32N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Trifarotene impurity 22 (CAS CATO-C4X-313222, C29H32N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Trifarotene impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H32N2O2 |
| Molecular Weight | 440.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Trifarotene Standards
- Trifarotene Impurity 3 (CAS CATO-C4X-31323)
- Trifarotene Impurity 6 (CAS CATO-C4X-31326)
- Trifarotene (CAS 895542-09-3)
- Trifarotene impurity 28 (CAS CATO-C4X-313228)
- Trifarotene Impurity 13 (CAS CATO-C4X-313213)
- Trifarotene Impurity 8 (CAS 895542-96-8)
- Trifarotene impurity 25 (CAS CATO-C4X-313225)
- Trifarotene impurity 16 (CAS CATO-C4X-313216)
Recommended Standards
- Gadoteridol impurity 36 (CAS CATO-C4X-225736)
- 3-Methoxy-7α-methyl-6β-(phenylsulfonyl) Estradiol (CAS 153004-09-2)
- Verapamil Impurity 44 (CAS CATO-C4X-177844)
- 3-Methoxy-7β-methyl-6β-(phenylsulfonyl) Estradiol (CAS 156137-95-0)
- Bezafibrate EP Impurity D (CAS 41859-58-9)
- Perindopril Impurity 93 (CAS CATO-C4X-125293)
- Indometacin Impurity 23 (CAS CATO-C4X-147023)
- Tert-butyl (3S,6S)-6-(((tert-butyldimethylsilyl)oxy)methyl)-3-hydroxy-4-methyl-3,6-dihydropyridine-1(2H)-carboxylate (CAS 1467157-45-4)
- D-Glucose-1,6 13C2-6-C-d2 (CAS 157171-80-7)
- (1S)-O,O'-([1,1'-binaphthalene]-2,2'-diyl) bis(dimethylcarbamothioate) (CAS 189084-88-6)
- 2-tert-Butyl 1-methyl 6-methoxy-3,4-dihydroisoquinoline-1,2(1H)-dicarboxylate (CAS 531556-16-8)
- (5-Bromopyridin-3-yl)(3-hydroxypyrrolidin-1-yl)methanone (CAS 1285344-38-8)
- Ataluren Impurity 4 (CAS CATO-C4X-30064)
- Uremic Pentapeptide (CAS 71494-20-7)
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