Trifarotene Impurity 8 CAS 895542-96-8
| CAS No. | 895542-96-8 |
| Molecular Formula | C19H19BrO5 |
| Molecular Weight | 407.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Trifarotene Impurity 8 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Trifarotene Impurity 8 (CAS 895542-96-8) is a certified pharmaceutical impurity reference standard with the molecular formula C19H19BrO5 and a molecular weight of 407.26 g/mol.
Trifarotene Impurity 8 (C19H19BrO5) contains a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H19BrO5 |
| Molecular Weight | 407.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
Related Trifarotene Standards
- Trifarotene impurity 25 (CAS CATO-C4X-313225)
- Trifarotene impurity 16 (CAS CATO-C4X-313216)
- Trifarotene Impurity 5 (CAS CATO-C4X-31325)
- Trifarotene impurity 28 (CAS CATO-C4X-313228)
- Trifarotene Impurity 4 (CAS CATO-C4X-31324)
- Trifarotene impurity 26 (CAS CATO-C4X-313226)
- Trifarotene impurity 21 (CAS CATO-C4X-313221)
- Trifarotene impurity 22 (CAS CATO-C4X-313222)
Recommended Standards
- Thalidomide-C5-Br (CAS 2411022-24-5)
- Ketoconazole Impurity 14 (CAS 170210-50-1)
- N-(2-Benzylbenzo[d]oxazol-5-yl)-4-bromobenzamide (CAS 785836-61-5)
- 2-(Benzyloxy)-6-(4-bromo-2-fluorophenyl)naphthalene (CAS 477860-11-0)
- Ornidazole Impurity 69 (CAS CATO-C4X-133169)
- Dapagliflozin Impurity 38 (CAS 2132-59-4)
- Ilaprazole Impurity 70 (CAS 2285346-40-7)
- 2-Iodopyrimidine-5-carbaldehyde (CAS 1461708-57-5)
- 2-((1-Phenyl-1H-pyrazolo[3,4-b]pyrazin-5-yl)amino)ethanol (CAS 87611-99-2)
- 5-Oxo-1-(3-pyridinylmethyl)-3-pyrrolidinecarboxylic acid (CAS 842958-29-6)
- 2,5-Dichloro-3-methylbenzoyl chloride (CAS 1806304-08-4)
- 3-(Difluoromethoxy)isonicotinonitrile (CAS 1805663-47-1)
- 3-Amino-2-(naphthalen-1-yl)propanoic acid (CAS 100393-37-1)
- Peptide 431 (CAS CATO-CPTD788431)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com