Vazegepant Impurity 27 CAS CATO-C4X-320027
| CAS No. | CATO-C4X-320027 |
| Molecular Formula | C23H22N6O4 |
| Molecular Weight | 446.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Vazegepant Impurity 27 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Vazegepant Impurity 27 (CAS CATO-C4X-320027, C23H22N6O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Vazegepant Impurity 27 (C23H22N6O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 446.46 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H22N6O4 |
| Molecular Weight | 446.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Vazegepant Standards
- Vazegepant Impurity 14 (CAS 928014-62-4)
- Vazegepant Impurity 3 (CAS CATO-C4X-32003)
- Vazegepant Impurity 16 (CAS CATO-C4X-320016)
- Vazegepant Impurity 10 (CAS CATO-C4X-320010)
- Vazegepant Impurity 2 (CAS CATO-C4X-32002)
- Vazegepant Impurity 26 (CAS 928014-64-6)
- Vazegepant Impurity 45 (CAS CATO-C4X-320045)
- Vazegepant Impurity 15 (CAS CATO-C4X-320015)
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