Vazegepant Impurity 14 CAS 928014-62-4
| CAS No. | 928014-62-4 |
| Molecular Formula | C26H27N5O4 |
| Molecular Weight | 473.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C26H27N5O4, Vazegepant Impurity 14 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 473.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Vazegepant Impurity 14 (CAS 928014-62-4, C26H27N5O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H27N5O4 |
| Molecular Weight | 473.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 5 |
Related Vazegepant Standards
- Vazegepant Impurity 3 (CAS CATO-C4X-32003)
- Vazegepant Impurity 16 (CAS CATO-C4X-320016)
- Vazegepant Impurity 10 (CAS CATO-C4X-320010)
- Vazegepant Impurity 2 (CAS CATO-C4X-32002)
- Vazegepant Impurity 26 (CAS 928014-64-6)
- Vazegepant Impurity 45 (CAS CATO-C4X-320045)
- Vazegepant Impurity 27 (CAS CATO-C4X-320027)
- Vazegepant Impurity 21 (CAS CATO-C4X-320021)
Recommended Standards
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- Dacomitinib Impurity 1 (CAS CATO-C4X-20861)
- Latanoprost EP Impurity D (CAS 2088449-88-9)
- Indobufen Impurity 51 Disodium Salt (CAS 203313-55-7(free base))
- 2-[(3-Pyridinylmethyl)amino]-1-butanol (CAS 869942-14-3)
- 2,4,5-Trifluoro-N,3-dihydroxybenzamide (CAS 1019128-07-4)
- 2-FLUORO-10H-PHENOTHIAZINE (CAS 397-58-0)
- 5-(Adamantan-1-yl)-4-allyl-4H-1,2,4-triazole-3-thiol (CAS 345987-96-4)
- 4-(4-tert-Butylphenyl)-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860612-43-7)
- Ethyl [1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate (CAS 1864014-92-5)
- Eledoisin Related Peptide (CAS 2990-43-4)
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