Orforglipron Impurity 17 CAS CATO-C4X-323417
| CAS No. | CATO-C4X-323417 |
| Molecular Formula | C23H28FN5O3 |
| Molecular Weight | 441.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 441.50 g/mol gives Orforglipron Impurity 17 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Orforglipron Impurity 17 (CAS CATO-C4X-323417, C23H28FN5O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Orforglipron Impurity 17 (C23H28FN5O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 441.50 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H28FN5O3 |
| Molecular Weight | 441.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Orforglipron Standards
- Orforglipron Impurity 13 (CAS 2212021-61-7)
- Orforglipron Impurity 12 (CAS 2212021-81-1)
- Orforglipron impurity 123 (CAS CATO-C4X-3234123)
- Orforglipron impurity 124 (CAS CATO-C4X-3234124)
- Orforglipron impurity 69 (CAS CATO-C4X-323469)
- Orforglipron impurity 75 (CAS CATO-C4X-323475)
- Orforglipron impurity 76 (CAS CATO-C4X-323476)
- Orforglipron impurity 77 (CAS CATO-C4X-323477)
Recommended Standards
- Ethyl 2-(2-(1-(6-(1H-imidazol-1-yl)pyrimidin-4-yl)piperidine-4-carboxamido)thiazol-4-yl)acetate (CAS 1351604-91-5)
- Bumetanide Impurity 24 (CAS CATO-C4X-198624)
- 2-((5-(Benzylthio)-1,3,4-thiadiazol-2-yl)thio)-N-(2-(trifluoromethyl)phenyl)acetamide (CAS 477331-27-4)
- NCGC00378430 (CAS 920650-00-6)
- Sorbitol impurity 4 (CAS 86334-50-1)
- Azelastine Impurity 30 (CAS 117078-70-3)
- Phenylephrine Impurity 75 (CAS CATO-C4X-146775)
- 2-Methyl-4a,5-dihydro-2H-indeno[1,2-c]pyridazin-3(4H)-one (CAS 69099-77-0)
- 3-(2,4-Dichlorophenyl)-5-((3-fluorobenzyl)thio)-4H-1,2,4-triazol-4-amine (CAS 585564-00-7)
- 1,1,1,2,2,3,3,4,4,5,5-Undecafluoro-6-iodohexane (CAS 335-50-2)
- 2-(Aminomethyl)-5-chloro-3-(difluoromethyl)-6-fluoropyridine (CAS 1805977-95-0)
- Benzo[d]thiazol-2-ylmethanamine hydrochloride (CAS 29198-41-2)
- Sodium (2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl phosphate (CAS 102783-59-5)
- Semaglutide impurity 38 (CAS CATO-C4X-222638)
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