HISTIDINE impurity 5 CAS CATO-C4X-32395
| CAS No. | CATO-C4X-32395 |
| Molecular Formula | C6H8N2O3 |
| Molecular Weight | 156.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, HISTIDINE impurity 5 (C6H8N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 156.14 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, HISTIDINE impurity 5 (CAS CATO-C4X-32395, C6H8N2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures HISTIDINE impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H8N2O3 |
| Molecular Weight | 156.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related HISTIDINE Standards
Recommended Standards
- O,O,O-trimethyl phosphorothioate (CAS 152-18-1)
- Resmetirom Impurity 3 (CAS 6629-04-5)
- 2,5-Dimethoxypyrimidin-4(3H)-one (CAS 370103-23-4)
- Pilocarpine Impurity 8 (CAS CATO-C4X-24018)
- Venetoclax Impurity 103 (CAS CATO-C4X-2495103)
- Calcitriol EP Impurity B (CAS 66791-71-7)
- Erlotinib Impurity 42 (CAS 501684-22-6)
- Neodymium(III) oxalate hydrate (CAS 28877-87-4)
- 3-(3-Ethynylphenyl)propan-1-ol (CAS 1098106-66-1)
- 3-(Furan-2-yl)-6-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 954254-90-1)
- N2,N2-Dimethyl-1H-benzo[d]imidazole-2,4-diamine (CAS 208773-19-7)
- 3-(4-Fluorophenyl)-5-((phenylselanyl)methyl)-4,5-dihydroisoxazole (CAS 833462-37-6)
- 2,5-Dimethyl-1-(2-methyl-4-nitrophenyl)-1h-pyrrole-3-carbaldehyde (CAS 347332-23-4)
- Endo-38a-Pro-Exenatide trifluoroacetate salt (CAS 1678416-95-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com