Venetoclax Impurity 103 CAS CATO-C4X-2495103
| CAS No. | CATO-C4X-2495103 |
| Molecular Formula | C12H17N3O5S |
| Molecular Weight | 315.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 315.35 g/mol gives Venetoclax Impurity 103 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Venetoclax Impurity 103 (CAS CATO-C4X-2495103, C12H17N3O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Venetoclax Impurity 103 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 315.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Venetoclax Impurity 103 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17N3O5S |
| Molecular Weight | 315.35 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Venetoclax Standards
- Venetoclax Impurity 1 (CAS 1228779-96-1)
- Venetoclax Impurity 102 (CAS CATO-C4X-2495102)
- Venetoclax Impurity 117 (CAS CATO-C4X-2495117)
- Venetoclax Impurity 123 (CAS CATO-C4X-2495123)
- Venetoclax Impurity 90 (CAS CATO-C4X-249590)
- Venetoclax Impurity 136 (CAS CATO-C4X-2495136)
- Venetoclax Impurity 138 (CAS CATO-C4X-2495138)
- Venetoclax Impurity 133 (CAS CATO-C4X-2495133)
Recommended Standards
- Nicorandil impurity 68 (CAS CATO-C4X-190768)
- Imipenem Impurity 116 (CAS CATO-C4X-1662116)
- Oxfendazole (CAS 53716-50-0)
- Entacapone Impurity 23 (CAS 1185241-19-3)
- Difamilast Impurity 3 (CAS 937782-02-0)
- Amiodarone Impurity 23 (CAS CATO-C4X-142523)
- Parecoxib Impurity 4 (CAS CATO-C4X-15914)
- 2-Benzyl 5-ethyl 1H-imidazole-2,5-dicarboxylate (CAS 851078-67-6)
- Erythromycin thiocyanate impurity C reduced derivative (CAS CATO-C4X-100167)
- 5-Amino-1-((2-methylthiazol-4-yl)methyl)-2',3',5',6'-tetrahydrospiro[indoline-3,4'-pyran]-2-one (CAS 1422069-55-3)
- 3-Methylphosphinicopropionic Acid Disodium Salt (CAS 66992-42-5)
- (S)-1-(2,4,5-trimethylphenyl)pentan-1-amine (CAS 1213466-46-6)
- 5'-Fluoro-2'-hydroxy-4-methoxychalcone (CAS 391-94-6)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
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