Fluticasone Furoate Impurity 6 CAS CATO-C4X-32546
| CAS No. | CATO-C4X-32546 |
| Molecular Formula | C52H54F4O12S2 |
| Molecular Weight | 1011.10 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 1011.10 g/mol gives Fluticasone Furoate Impurity 6 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Fluticasone Furoate Impurity 6 (CAS CATO-C4X-32546, C52H54F4O12S2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Fluticasone Furoate Impurity 6 (C52H54F4O12S2) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 24.0, corresponding to approximately 24 ring(s) or double-bond equivalent(s). With a molecular weight of 1011.10 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C52H54F4O12S2 |
| Molecular Weight | 1011.10 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Sulfur Atoms | 2 |
Related Fluticasone Standards
- Fluticasone Impurity 30 (CAS CATO-C4X-165030)
- Fluticasone Furoate Impurity 8 (CAS CATO-C4X-32548)
- Fluticasone Furoate Impurity 7 (CAS CATO-C4X-32547)
- Fluticasone Propionate EP Impurity I (CAS 960071-64-1)
- Fluticasone Impurity 36 (CAS 192191-51-8)
- Fluticasone Propionate EP Impurity H (CAS 201812-64-8)
- Fluticasone Furoate EP Impurity L (CAS CATO-C4X-165029)
- Fluticasone Furoate Impurity 9 (CAS CATO-C4X-32549)
Recommended Standards
- Palladium(1+), [2′-(amino-κN)[1,1′-biphenyl]-2-yl-κC][[3,6-dimethoxy-2′,4′,6′-tris(1-methylethyl)[1,1′-biphenyl]-2-yl-κC1′]bis(tricyclo[3.3.1.13,7]dec-1-yl)phosphine-κP]-, methanesulfonate (CAS 1435520-71-0)
- H-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH (CAS CATO-CPTD788759)
- DSPE-PEG4-acid (CAS 2112738-58-4)
- Yttriumoxalatetetrahydrate (CAS 867-68-5)
- Eldecalcitol Impurity 2 (CAS 201854-22-0)
- Luliconazole impurity 22 (CAS CATO-C4X-285322)
- Fenofibrate Impurity N4 (CAS 66938-32-7)
- 5-Bromo-3-chloro-2-methoxypyridine-4-carboxaldehyde (CAS 1224604-20-9)
- 4-(2-Chloropyrido[3,2-d]pyrimidin-4-yl)thiomorpholine 1,1-dioxide (CAS 39551-64-9)
- 3-(Benzylimino)indolin-2-one (CAS 147951-01-7)
- 3-(Naphthalen-2-yl)benzofuran-5-ol (CAS 1573547-49-5)
- Dimethyl((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)phosphine oxide (CAS 2444346-69-2)
- Ethyl 5-(4-(4-(3,5-dimethylisoxazole-4-carbonyl)piperazin-1-yl)phenyl)-1-o-tolyl-1H-pyrazole-3-carboxylate (CAS 1007477-05-5)
- Semaglutide impurity 92 (CAS CATO-C4X-222692)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com